SEPTIN14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SEPTIN14 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SEPTIN14 at tissue level.

III. Associated gene sets

GO_1905719Biological processprotein localization to perinuclear region of cytoplasm
GO_0061640Biological processcytoskeleton-dependent cytokinesis
GO_0001764Biological processneuron migration
GO_0008104Biological processprotein localization
GO_0007286Biological processspermatid development
GO_0005856Cellular componentcytoskeleton
GO_0032153Cellular componentcell division site
GO_0001669Cellular componentacrosomal vesicle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0043204Cellular componentperikaryon
GO_0030425Cellular componentdendrite
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0031105Cellular componentseptin complex
GO_0005737Cellular componentcytoplasm
GO_0005940Cellular componentseptin ring
GO_0030424Cellular componentaxon
GO_0060090Molecular functionmolecular adaptor activity
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameSEPTIN14
Protein nameSeptin-14
SynonymsSEPT14
DescriptionFUNCTION: Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity). Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments . .

AccessionsQ6ZU15
ENST00000388975.4