I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 6 studies | 31% ± 13% | |
| astrocyte | 5 studies | 29% ± 12% | |
| glutamatergic neuron | 4 studies | 40% ± 16% | |
| chondrocyte | 3 studies | 40% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 6 studies | 31% ± 13% | |
| astrocyte | 5 studies | 29% ± 12% | |
| glutamatergic neuron | 4 studies | 40% ± 16% | |
| chondrocyte | 3 studies | 40% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 23% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 98% | 802.46 | 241 / 245 | 94% | 9.69 | 473 / 502 |
| brain | 93% | 508.16 | 2455 / 2642 | 73% | 3.30 | 513 / 705 |
| lung | 99% | 621.87 | 575 / 578 | 50% | 5.77 | 583 / 1155 |
| esophagus | 87% | 219.31 | 1256 / 1445 | 55% | 7.16 | 101 / 183 |
| thymus | 96% | 383.67 | 628 / 653 | 30% | 2.84 | 179 / 605 |
| intestine | 93% | 341.94 | 901 / 966 | 17% | 0.86 | 92 / 527 |
| ovary | 61% | 155.01 | 109 / 180 | 44% | 4.48 | 191 / 430 |
| spleen | 100% | 1123.27 | 241 / 241 | 0% | 0 | 0 / 0 |
| breast | 61% | 301.23 | 281 / 459 | 38% | 3.31 | 428 / 1118 |
| skin | 67% | 192.64 | 1217 / 1809 | 31% | 3.36 | 147 / 472 |
| adrenal gland | 29% | 58.55 | 74 / 258 | 63% | 5.41 | 144 / 230 |
| stomach | 72% | 144.52 | 259 / 359 | 16% | 1.03 | 46 / 286 |
| kidney | 78% | 142.13 | 69 / 89 | 9% | 0.46 | 81 / 901 |
| bladder | 71% | 235.24 | 15 / 21 | 15% | 1.31 | 76 / 504 |
| uterus | 44% | 387.54 | 75 / 170 | 41% | 3.77 | 189 / 459 |
| heart | 83% | 273.13 | 715 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 77% | 327.33 | 1023 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 4.15 | 27 / 45 |
| eye | 0% | 0 | 0 / 0 | 26% | 1.09 | 21 / 80 |
| pancreas | 2% | 2.54 | 7 / 328 | 22% | 1.11 | 39 / 178 |
| peripheral blood | 24% | 40.70 | 222 / 929 | 0% | 0 | 0 / 0 |
| adipose | 23% | 37.68 | 273 / 1204 | 0% | 0 | 0 / 0 |
| liver | 5% | 8.45 | 11 / 226 | 9% | 0.52 | 38 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.71 | 3 / 29 |
| muscle | 2% | 2.11 | 13 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007416 | Biological process | synapse assembly |
| GO_0060219 | Biological process | camera-type eye photoreceptor cell differentiation |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0010842 | Biological process | retina layer formation |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SDK2 |
| Protein name | Sidekick cell adhesion molecule 2 Protein sidekick-2 |
| Synonyms | KIAA1514 |
| Description | FUNCTION: Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3-ACs. Formation of synapses between these two cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions. . |
| Accessions | ENST00000392650.8 [Q58EX2-1] ENST00000424778.1 H7C2P2 Q58EX2 |
