Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell of lymphatic vessel | 17 studies | 29% ± 10% | |
| glutamatergic neuron | 10 studies | 46% ± 21% | |
| neuron | 7 studies | 28% ± 7% | |
| interneuron | 6 studies | 34% ± 20% | |
| GABAergic neuron | 6 studies | 38% ± 15% | |
| amacrine cell | 5 studies | 31% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 7 studies | 39% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 6658.46 | 2491 / 2642 | 96% | 28.88 | 678 / 705 |
| thymus | 96% | 1273.58 | 629 / 653 | 48% | 1.23 | 290 / 605 |
| adrenal gland | 31% | 386.43 | 80 / 258 | 75% | 48.85 | 173 / 230 |
| muscle | 99% | 2249.17 | 796 / 803 | 0% | 0 | 0 / 0 |
| breast | 62% | 496.60 | 283 / 459 | 11% | 0.26 | 121 / 1118 |
| ovary | 30% | 155.53 | 54 / 180 | 40% | 1.10 | 171 / 430 |
| adipose | 61% | 420.95 | 732 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 34% | 173.46 | 57 / 170 | 16% | 0.77 | 73 / 459 |
| intestine | 41% | 253.81 | 393 / 966 | 7% | 0.24 | 37 / 527 |
| esophagus | 22% | 128.95 | 315 / 1445 | 22% | 0.63 | 40 / 183 |
| pancreas | 5% | 26.59 | 18 / 328 | 38% | 1.36 | 67 / 178 |
| kidney | 7% | 42.71 | 6 / 89 | 35% | 0.77 | 313 / 901 |
| lung | 28% | 153.07 | 159 / 578 | 10% | 0.31 | 120 / 1155 |
| skin | 31% | 196.43 | 567 / 1809 | 4% | 0.14 | 17 / 472 |
| bladder | 29% | 134.52 | 6 / 21 | 4% | 0.13 | 18 / 504 |
| prostate | 13% | 94.62 | 31 / 245 | 13% | 0.28 | 64 / 502 |
| stomach | 11% | 55.84 | 39 / 359 | 10% | 0.34 | 30 / 286 |
| eye | 0% | 0 | 0 / 0 | 19% | 0.47 | 15 / 80 |
| heart | 8% | 42.26 | 66 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 6% | 40.93 | 78 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 3% | 0.07 | 11 / 406 |
| spleen | 2% | 14.18 | 6 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0086012 | Biological process | membrane depolarization during cardiac muscle cell action potential |
| GO_2000649 | Biological process | regulation of sodium ion transmembrane transporter activity |
| GO_0086015 | Biological process | SA node cell action potential |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0051899 | Biological process | membrane depolarization |
| GO_0086002 | Biological process | cardiac muscle cell action potential involved in contraction |
| GO_0010460 | Biological process | positive regulation of heart rate |
| GO_0086005 | Biological process | ventricular cardiac muscle cell action potential |
| GO_0060373 | Biological process | regulation of ventricular cardiac muscle cell membrane depolarization |
| GO_0086014 | Biological process | atrial cardiac muscle cell action potential |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0010765 | Biological process | positive regulation of sodium ion transport |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0060371 | Biological process | regulation of atrial cardiac muscle cell membrane depolarization |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0086010 | Biological process | membrane depolarization during action potential |
| GO_0007399 | Biological process | nervous system development |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0030018 | Cellular component | Z disc |
| GO_0001518 | Cellular component | voltage-gated sodium channel complex |
| GO_0086006 | Molecular function | voltage-gated sodium channel activity involved in cardiac muscle cell action potential |
| GO_0019871 | Molecular function | sodium channel inhibitor activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0017080 | Molecular function | sodium channel regulator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SCN3B |
| Protein name | Sodium voltage-gated channel beta subunit 3 Sodium channel regulatory subunit beta-3 Sodium channel subunit beta-3 |
| Synonyms | KIAA1158 |
| Description | FUNCTION: Voltage-gated sodium channels regulatory subunit that modulates channel gating kinetics . Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity). . FUNCTION: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons. . |
| Accessions | A0A590UJQ5 ENST00000667790.1 A0A590UJ13 Q9NY72 ENST00000299333.8 ENST00000659826.1 ENST00000657123.1 ENST00000657191.1 ENST00000530277.5 ENST00000392770.6 |
