SCAMP5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045806Biological processnegative regulation of endocytosis
GO_0015031Biological processprotein transport
GO_0045956Biological processpositive regulation of calcium ion-dependent exocytosis
GO_0001819Biological processpositive regulation of cytokine production
GO_0006887Biological processexocytosis
GO_0034976Biological processresponse to endoplasmic reticulum stress
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0000139Cellular componentGolgi membrane
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0044877Molecular functionprotein-containing complex binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSCAMP5
Protein nameSecretory carrier-associated membrane protein (Secretory carrier membrane protein)
Secretory carrier-associated membrane protein 5 (Secretory carrier membrane protein 5) (hSCAMP5)
Synonyms
DescriptionFUNCTION: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway. .

AccessionsENST00000566872.5
H3BNH7
ENST00000564779.5
ENST00000562765.5
ENST00000565989.5
A0A0A8K8F5
ENST00000568018.5
H3BNW6
ENST00000562327.5
H3BS22
ENST00000568423.5
H3BMY4
ENST00000361900.10 [Q8TAC9-1]
H3BP89
ENST00000567529.1
H3BNB3
H3BU33
H3BTD1
H3BT30
ENST00000564491.5
ENST00000562212.5 [Q8TAC9-2]
ENST00000568119.5
ENST00000568081.1
ENST00000567920.5
Q8TAC9
ENST00000425597.8 [Q8TAC9-1]