Name | Number of supported studies | Average coverage | |
---|---|---|---|
CD4-positive, alpha-beta T cell | 7 studies | 21% ± 5% | |
oligodendrocyte | 5 studies | 21% ± 5% | |
retinal ganglion cell | 4 studies | 58% ± 25% | |
T cell | 4 studies | 24% ± 7% | |
epithelial cell | 4 studies | 28% ± 7% | |
GABAergic neuron | 4 studies | 37% ± 6% | |
glutamatergic neuron | 4 studies | 43% ± 15% | |
oligodendrocyte precursor cell | 4 studies | 28% ± 10% | |
ionocyte | 3 studies | 28% ± 3% | |
endothelial cell | 3 studies | 21% ± 2% | |
regulatory T cell | 3 studies | 21% ± 1% | |
B cell | 3 studies | 19% ± 2% | |
neuron | 3 studies | 26% ± 7% | |
naive B cell | 3 studies | 16% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 3017.82 | 245 / 245 | 100% | 67.06 | 502 / 502 |
brain | 100% | 2494.26 | 2639 / 2642 | 100% | 32.81 | 704 / 705 |
esophagus | 99% | 1836.88 | 1435 / 1445 | 100% | 27.92 | 183 / 183 |
ovary | 100% | 1234.55 | 180 / 180 | 99% | 18.97 | 427 / 430 |
lung | 99% | 1764.21 | 573 / 578 | 99% | 32.20 | 1141 / 1155 |
adrenal gland | 100% | 2615.59 | 258 / 258 | 97% | 26.82 | 223 / 230 |
thymus | 100% | 1098.83 | 650 / 653 | 97% | 19.70 | 588 / 605 |
liver | 100% | 7295.92 | 226 / 226 | 96% | 32.14 | 390 / 406 |
bladder | 100% | 1955.81 | 21 / 21 | 95% | 21.45 | 480 / 504 |
intestine | 100% | 1262.86 | 965 / 966 | 95% | 15.70 | 502 / 527 |
stomach | 100% | 1241.47 | 359 / 359 | 95% | 15.53 | 272 / 286 |
breast | 100% | 1748.51 | 459 / 459 | 95% | 18.56 | 1058 / 1118 |
pancreas | 96% | 844.05 | 314 / 328 | 98% | 14.59 | 175 / 178 |
uterus | 99% | 1085.05 | 169 / 170 | 91% | 14.08 | 417 / 459 |
kidney | 100% | 1527.74 | 89 / 89 | 90% | 17.15 | 807 / 901 |
skin | 99% | 1490.43 | 1798 / 1809 | 82% | 13.32 | 387 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.14 | 1 / 1 |
adipose | 100% | 1273.95 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1108.34 | 1325 / 1335 | 0% | 0 | 0 / 0 |
spleen | 91% | 534.48 | 220 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 13.01 | 40 / 45 |
heart | 88% | 964.82 | 758 / 861 | 0% | 0 | 0 / 0 |
muscle | 63% | 306.65 | 502 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 5.17 | 17 / 29 |
eye | 0% | 0 | 0 / 0 | 50% | 4.53 | 40 / 80 |
peripheral blood | 43% | 723.03 | 402 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0033490 | Biological process | cholesterol biosynthetic process via lathosterol |
GO_0006629 | Biological process | lipid metabolic process |
GO_0033489 | Biological process | cholesterol biosynthetic process via desmosterol |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0000248 | Molecular function | C-5 sterol desaturase activity |
GO_0005506 | Molecular function | iron ion binding |
GO_0050046 | Molecular function | delta7-sterol 5(6)-desaturase activity |
Gene name | SC5D |
Protein name | Sterol-C5-desaturase Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase) |
Synonyms | SC5DL |
Description | FUNCTION: Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol in cholesterol biosynthesis. . |
Accessions | ENST00000527762.5 E9PPW5 E9PQ91 O75845 ENST00000534230.5 ENST00000392789.2 ENST00000264027.9 |