Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| CD4-positive, alpha-beta T cell | 7 studies | 21% ± 5% | |
| oligodendrocyte | 5 studies | 21% ± 5% | |
| retinal ganglion cell | 4 studies | 58% ± 25% | |
| T cell | 4 studies | 24% ± 7% | |
| epithelial cell | 4 studies | 28% ± 7% | |
| GABAergic neuron | 4 studies | 37% ± 6% | |
| glutamatergic neuron | 4 studies | 43% ± 15% | |
| oligodendrocyte precursor cell | 4 studies | 28% ± 10% | |
| ionocyte | 3 studies | 28% ± 3% | |
| endothelial cell | 3 studies | 21% ± 2% | |
| regulatory T cell | 3 studies | 21% ± 1% | |
| B cell | 3 studies | 19% ± 2% | |
| neuron | 3 studies | 26% ± 7% | |
| naive B cell | 3 studies | 16% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 3017.82 | 245 / 245 | 100% | 67.06 | 502 / 502 |
| brain | 100% | 2494.26 | 2639 / 2642 | 100% | 32.81 | 704 / 705 |
| esophagus | 99% | 1836.88 | 1435 / 1445 | 100% | 27.92 | 183 / 183 |
| ovary | 100% | 1234.55 | 180 / 180 | 99% | 18.97 | 427 / 430 |
| lung | 99% | 1764.21 | 573 / 578 | 99% | 32.20 | 1141 / 1155 |
| adrenal gland | 100% | 2615.59 | 258 / 258 | 97% | 26.82 | 223 / 230 |
| thymus | 100% | 1098.83 | 650 / 653 | 97% | 19.70 | 588 / 605 |
| liver | 100% | 7295.92 | 226 / 226 | 96% | 32.14 | 390 / 406 |
| bladder | 100% | 1955.81 | 21 / 21 | 95% | 21.45 | 480 / 504 |
| intestine | 100% | 1262.86 | 965 / 966 | 95% | 15.70 | 502 / 527 |
| stomach | 100% | 1241.47 | 359 / 359 | 95% | 15.53 | 272 / 286 |
| breast | 100% | 1748.51 | 459 / 459 | 95% | 18.56 | 1058 / 1118 |
| pancreas | 96% | 844.05 | 314 / 328 | 98% | 14.59 | 175 / 178 |
| uterus | 99% | 1085.05 | 169 / 170 | 91% | 14.08 | 417 / 459 |
| kidney | 100% | 1527.74 | 89 / 89 | 90% | 17.15 | 807 / 901 |
| skin | 99% | 1490.43 | 1798 / 1809 | 82% | 13.32 | 387 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.14 | 1 / 1 |
| adipose | 100% | 1273.95 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1108.34 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 91% | 534.48 | 220 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 13.01 | 40 / 45 |
| heart | 88% | 964.82 | 758 / 861 | 0% | 0 | 0 / 0 |
| muscle | 63% | 306.65 | 502 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 59% | 5.17 | 17 / 29 |
| eye | 0% | 0 | 0 / 0 | 50% | 4.53 | 40 / 80 |
| peripheral blood | 43% | 723.03 | 402 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0033490 | Biological process | cholesterol biosynthetic process via lathosterol |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0033489 | Biological process | cholesterol biosynthetic process via desmosterol |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0000248 | Molecular function | C-5 sterol desaturase activity |
| GO_0005506 | Molecular function | iron ion binding |
| GO_0050046 | Molecular function | delta7-sterol 5(6)-desaturase activity |
| Gene name | SC5D |
| Protein name | Sterol-C5-desaturase Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase) |
| Synonyms | SC5DL |
| Description | FUNCTION: Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol in cholesterol biosynthesis. . |
| Accessions | ENST00000527762.5 E9PPW5 E9PQ91 O75845 ENST00000534230.5 ENST00000392789.2 ENST00000264027.9 |