SC5D report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0033490Biological processcholesterol biosynthetic process via lathosterol
GO_0006629Biological processlipid metabolic process
GO_0033489Biological processcholesterol biosynthetic process via desmosterol
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0000248Molecular functionC-5 sterol desaturase activity
GO_0005506Molecular functioniron ion binding
GO_0050046Molecular functiondelta7-sterol 5(6)-desaturase activity

IV. Literature review

[source]
Gene nameSC5D
Protein nameSterol-C5-desaturase
Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase)
SynonymsSC5DL
DescriptionFUNCTION: Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol in cholesterol biosynthesis. .

AccessionsENST00000527762.5
E9PPW5
E9PQ91
O75845
ENST00000534230.5
ENST00000392789.2
ENST00000264027.9