RRM2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RRM2 at tissue level.

III. Associated gene sets

GO_1900087Biological processpositive regulation of G1/S transition of mitotic cell cycle
GO_0051290Biological processprotein heterotetramerization
GO_0009185Biological processribonucleoside diphosphate metabolic process
GO_0001824Biological processblastocyst development
GO_0009263Biological processdeoxyribonucleotide biosynthetic process
GO_0009265Biological process2'-deoxyribonucleotide biosynthetic process
GO_0005829Cellular componentcytosol
GO_0005971Cellular componentribonucleoside-diphosphate reductase complex
GO_0005634Cellular componentnucleus
GO_0004748Molecular functionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO_0042803Molecular functionprotein homodimerization activity
GO_0005515Molecular functionprotein binding
GO_0008199Molecular functionferric iron binding

IV. Literature review

[source]
Gene nameRRM2
Protein nameRibonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain)
Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit)
Ribonucleotide reductase regulatory subunit M2
SynonymsRR2
DescriptionFUNCTION: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

AccessionsENST00000646978.1
ENST00000641198.1 [P31350-1]
A0A7P0SBL1
ENST00000304567.10 [P31350-1]
P31350
A0A2R8Y837
A0A286YFD6
ENST00000641498.1
ENST00000360566.6 [P31350-2]
ENST00000615152.5