Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 23% ± 7% | |
| natural killer cell | 5 studies | 17% ± 1% | |
| plasmablast | 3 studies | 45% ± 15% | |
| B cell | 3 studies | 18% ± 3% | |
| CD4-positive, alpha-beta T cell | 3 studies | 19% ± 1% | |
| endothelial cell | 3 studies | 18% ± 3% | |
| dendritic cell | 3 studies | 26% ± 6% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 3% |
Insufficient scRNA-seq data for expression of RNASEH1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 799.74 | 1445 / 1445 | 100% | 18.55 | 183 / 183 |
| intestine | 100% | 778.09 | 966 / 966 | 100% | 16.00 | 527 / 527 |
| prostate | 100% | 639.78 | 245 / 245 | 100% | 14.61 | 501 / 502 |
| ovary | 100% | 645.78 | 180 / 180 | 100% | 14.71 | 429 / 430 |
| breast | 100% | 824.50 | 459 / 459 | 100% | 17.66 | 1115 / 1118 |
| lung | 100% | 732.32 | 576 / 578 | 100% | 16.98 | 1153 / 1155 |
| stomach | 100% | 607.40 | 358 / 359 | 100% | 15.71 | 285 / 286 |
| thymus | 100% | 675.43 | 652 / 653 | 99% | 13.80 | 601 / 605 |
| pancreas | 100% | 471.45 | 327 / 328 | 99% | 13.97 | 177 / 178 |
| uterus | 100% | 815.79 | 170 / 170 | 99% | 16.61 | 455 / 459 |
| bladder | 100% | 805.48 | 21 / 21 | 99% | 14.75 | 499 / 504 |
| skin | 100% | 1100.69 | 1809 / 1809 | 99% | 21.61 | 467 / 472 |
| brain | 99% | 526.93 | 2612 / 2642 | 100% | 21.07 | 705 / 705 |
| kidney | 100% | 571.35 | 89 / 89 | 98% | 12.02 | 883 / 901 |
| adrenal gland | 100% | 757.75 | 258 / 258 | 97% | 15.91 | 222 / 230 |
| liver | 100% | 481.10 | 225 / 226 | 94% | 8.52 | 382 / 406 |
| adipose | 100% | 853.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 867.33 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.50 | 29 / 29 |
| muscle | 100% | 990.24 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 674.13 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.41 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.86 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 13.02 | 79 / 80 |
| heart | 97% | 728.57 | 833 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 75% | 553.17 | 698 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043137 | Biological process | DNA replication, removal of RNA primer |
| GO_0006401 | Biological process | RNA catabolic process |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0003723 | Molecular function | RNA binding |
| GO_0004523 | Molecular function | RNA-DNA hybrid ribonuclease activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004540 | Molecular function | RNA nuclease activity |
| GO_0003676 | Molecular function | nucleic acid binding |
| GO_0000287 | Molecular function | magnesium ion binding |
| Gene name | RNASEH1 |
| Protein name | Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) Ribonuclease H1 |
| Synonyms | RNH1 |
| Description | FUNCTION: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids . Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II . . |
| Accessions | ENST00000436842.5 ENST00000315212.4 F8WD93 ENST00000454734.1 O60930 F8WBP0 |
