Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 19 studies | 35% ± 14% | |
| monocyte | 9 studies | 36% ± 18% | |
| myeloid cell | 6 studies | 43% ± 28% | |
| dendritic cell | 5 studies | 30% ± 12% | |
| conventional dendritic cell | 5 studies | 34% ± 11% | |
| hematopoietic precursor cell | 3 studies | 63% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 90% | 377.72 | 523 / 578 | 74% | 5.82 | 853 / 1155 |
| adrenal gland | 86% | 176.89 | 222 / 258 | 37% | 4.00 | 86 / 230 |
| ovary | 40% | 38.24 | 72 / 180 | 80% | 5.87 | 343 / 430 |
| bladder | 71% | 85.24 | 15 / 21 | 46% | 3.30 | 233 / 504 |
| brain | 35% | 49.04 | 930 / 2642 | 80% | 21.27 | 562 / 705 |
| breast | 50% | 46.87 | 230 / 459 | 63% | 3.10 | 700 / 1118 |
| pancreas | 27% | 23.43 | 87 / 328 | 80% | 7.05 | 142 / 178 |
| uterus | 48% | 44.58 | 81 / 170 | 52% | 2.97 | 237 / 459 |
| spleen | 97% | 1007.47 | 234 / 241 | 0% | 0 | 0 / 0 |
| kidney | 28% | 41.38 | 25 / 89 | 68% | 5.04 | 609 / 901 |
| stomach | 39% | 48.11 | 140 / 359 | 54% | 5.95 | 155 / 286 |
| intestine | 45% | 48.41 | 435 / 966 | 43% | 2.44 | 229 / 527 |
| esophagus | 37% | 36.54 | 537 / 1445 | 48% | 9.88 | 87 / 183 |
| peripheral blood | 81% | 6251.88 | 755 / 929 | 0% | 0 | 0 / 0 |
| adipose | 68% | 137.18 | 818 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 29% | 22.24 | 192 / 653 | 37% | 1.65 | 221 / 605 |
| skin | 8% | 5.12 | 151 / 1809 | 54% | 3.90 | 256 / 472 |
| blood vessel | 59% | 91.25 | 789 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 56% | 3.25 | 25 / 45 |
| prostate | 43% | 48.49 | 106 / 245 | 8% | 0.25 | 38 / 502 |
| heart | 48% | 61.62 | 416 / 861 | 0% | 0 | 0 / 0 |
| liver | 28% | 33.75 | 63 / 226 | 18% | 1.96 | 73 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 2.45 | 8 / 29 |
| muscle | 8% | 5.99 | 68 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.10 | 3 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0050829 | Biological process | defense response to Gram-negative bacterium |
| GO_0051607 | Biological process | defense response to virus |
| GO_0002227 | Biological process | innate immune response in mucosa |
| GO_0043152 | Biological process | induction of bacterial agglutination |
| GO_0050830 | Biological process | defense response to Gram-positive bacterium |
| GO_0006935 | Biological process | chemotaxis |
| GO_0006401 | Biological process | RNA catabolic process |
| GO_0035578 | Cellular component | azurophil granule lumen |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0004522 | Molecular function | ribonuclease A activity |
| GO_0001530 | Molecular function | lipopolysaccharide binding |
| GO_0016829 | Molecular function | lyase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004540 | Molecular function | RNA nuclease activity |
| GO_0003676 | Molecular function | nucleic acid binding |
| Gene name | RNASE2 |
| Protein name | Non-secretory ribonuclease (EC 4.6.1.18) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2) (Ribonuclease US) Non-secretory ribonuclease (EC 4.6.1.18) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (Ribonuclease US) |
| Synonyms | RNS2 RAF3 hCG_1778873 EDN |
| Description | FUNCTION: This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. . |
| Accessions | ENST00000304625.3 W0UV60 P10153 |