RIT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007265Biological processRas protein signal transduction
GO_0005886Cellular componentplasma membrane
GO_0019003Molecular functionGDP binding
GO_0005525Molecular functionGTP binding
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding
GO_0003925Molecular functionG protein activity
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRIT1
Protein nameRas like without CAAX 1
GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)
SynonymsROC1
RIBB
RIT
DescriptionFUNCTION: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. .

AccessionsQ92963
ENST00000539040.6 [Q92963-2]
V9GY29
ENST00000368322.7 [Q92963-3]
ENST00000651853.1
V9GYC3
A0A994J480
A0A494C0U3
ENST00000704061.1
ENST00000461050.6
ENST00000609492.1
A0A494C0S1
ENST00000651833.1
ENST00000368323.8 [Q92963-1]