Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 21% ± 5% | |
classical monocyte | 9 studies | 27% ± 11% | |
macrophage | 7 studies | 22% ± 4% | |
conventional dendritic cell | 5 studies | 22% ± 7% | |
platelet | 5 studies | 20% ± 4% | |
monocyte | 4 studies | 19% ± 4% | |
non-classical monocyte | 4 studies | 27% ± 7% | |
epithelial cell | 4 studies | 33% ± 8% | |
neutrophil | 3 studies | 18% ± 2% | |
myeloid cell | 3 studies | 29% ± 11% | |
endothelial cell of vascular tree | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 4 studies | 22% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1792.61 | 459 / 459 | 100% | 37.71 | 1117 / 1118 |
prostate | 100% | 1590.82 | 245 / 245 | 100% | 19.65 | 501 / 502 |
brain | 100% | 906.05 | 2634 / 2642 | 100% | 29.81 | 705 / 705 |
esophagus | 100% | 2119.58 | 1445 / 1445 | 99% | 26.95 | 182 / 183 |
bladder | 100% | 1971.48 | 21 / 21 | 99% | 29.66 | 501 / 504 |
lung | 100% | 2634.08 | 578 / 578 | 99% | 53.98 | 1148 / 1155 |
uterus | 100% | 1480.21 | 170 / 170 | 99% | 34.34 | 456 / 459 |
thymus | 100% | 1429.99 | 653 / 653 | 99% | 23.28 | 601 / 605 |
skin | 100% | 1433.38 | 1809 / 1809 | 99% | 31.81 | 466 / 472 |
ovary | 100% | 1214.79 | 180 / 180 | 99% | 17.26 | 424 / 430 |
kidney | 100% | 1918.56 | 89 / 89 | 98% | 53.80 | 880 / 901 |
intestine | 100% | 1526.67 | 966 / 966 | 98% | 15.87 | 514 / 527 |
stomach | 100% | 1574.67 | 359 / 359 | 96% | 14.98 | 275 / 286 |
pancreas | 97% | 604.24 | 318 / 328 | 99% | 25.42 | 176 / 178 |
adrenal gland | 100% | 1415.29 | 258 / 258 | 92% | 14.31 | 212 / 230 |
liver | 95% | 624.45 | 215 / 226 | 76% | 11.10 | 307 / 406 |
adipose | 100% | 1917.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1731.44 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 25.08 | 29 / 29 |
spleen | 100% | 2513.82 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 22.36 | 1 / 1 |
peripheral blood | 100% | 3315.66 | 928 / 929 | 0% | 0 | 0 / 0 |
heart | 100% | 1006.70 | 858 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 529.54 | 763 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 86% | 13.84 | 69 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0005886 | Cellular component | plasma membrane |
GO_0019003 | Molecular function | GDP binding |
GO_0005525 | Molecular function | GTP binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
GO_0003925 | Molecular function | G protein activity |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RIT1 |
Protein name | Ras like without CAAX 1 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) |
Synonyms | ROC1 RIBB RIT |
Description | FUNCTION: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. . |
Accessions | Q92963 ENST00000539040.6 [Q92963-2] V9GY29 ENST00000368322.7 [Q92963-3] ENST00000651853.1 V9GYC3 A0A994J480 A0A494C0U3 ENST00000704061.1 ENST00000461050.6 ENST00000609492.1 A0A494C0S1 ENST00000651833.1 ENST00000368323.8 [Q92963-1] |