Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 30 studies | 62% ± 23% | |
smooth muscle cell | 19 studies | 42% ± 23% | |
endothelial cell | 14 studies | 39% ± 16% | |
fibroblast | 6 studies | 28% ± 11% | |
capillary endothelial cell | 5 studies | 30% ± 24% | |
vein endothelial cell | 5 studies | 45% ± 30% | |
endothelial cell of artery | 4 studies | 51% ± 29% | |
astrocyte | 4 studies | 32% ± 17% | |
myofibroblast cell | 3 studies | 54% ± 28% | |
muscle cell | 3 studies | 36% ± 20% | |
GABAergic neuron | 3 studies | 36% ± 9% | |
glutamatergic neuron | 3 studies | 36% ± 2% |
Insufficient scRNA-seq data for expression of RGS5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 42433.00 | 652 / 653 | 89% | 210.91 | 536 / 605 |
prostate | 97% | 19844.02 | 238 / 245 | 88% | 74.19 | 440 / 502 |
adrenal gland | 80% | 12970.14 | 207 / 258 | 97% | 2262.40 | 222 / 230 |
brain | 84% | 13550.75 | 2222 / 2642 | 90% | 66.35 | 634 / 705 |
breast | 90% | 15553.80 | 413 / 459 | 79% | 98.31 | 882 / 1118 |
stomach | 93% | 14174.07 | 333 / 359 | 75% | 95.24 | 214 / 286 |
esophagus | 78% | 17154.65 | 1123 / 1445 | 75% | 82.05 | 138 / 183 |
bladder | 100% | 24292.19 | 21 / 21 | 51% | 34.77 | 257 / 504 |
intestine | 85% | 18912.94 | 824 / 966 | 60% | 50.04 | 316 / 527 |
kidney | 51% | 8411.64 | 45 / 89 | 80% | 774.15 | 721 / 901 |
lung | 69% | 9406.38 | 399 / 578 | 56% | 42.11 | 650 / 1155 |
uterus | 92% | 15767.32 | 156 / 170 | 32% | 21.56 | 146 / 459 |
blood vessel | 100% | 231548.62 | 1335 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 25147.72 | 843 / 861 | 0% | 0 | 0 / 0 |
muscle | 97% | 15054.81 | 778 / 803 | 0% | 0 | 0 / 0 |
adipose | 97% | 30646.80 | 1166 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 8% | 516.72 | 25 / 328 | 82% | 83.01 | 146 / 178 |
liver | 1% | 56.63 | 2 / 226 | 66% | 46.42 | 266 / 406 |
skin | 23% | 2121.71 | 408 / 1809 | 33% | 72.51 | 157 / 472 |
ovary | 22% | 1879.05 | 40 / 180 | 31% | 12.73 | 132 / 430 |
tonsil | 0% | 0 | 0 / 0 | 42% | 21.74 | 19 / 45 |
eye | 0% | 0 | 0 / 0 | 24% | 10.65 | 19 / 80 |
spleen | 9% | 638.88 | 21 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 2.24 | 2 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0008277 | Biological process | regulation of G protein-coupled receptor signaling pathway |
GO_0009968 | Biological process | negative regulation of signal transduction |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005515 | Molecular function | protein binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RGS5 |
Protein name | Regulator of G-protein signaling 5 (RGS5) Regulator of G-protein signaling 5 Regulator of G protein signaling 5 |
Synonyms | hCG_15193 |
Description | FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity). . FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. . |
Accessions | ENST00000527988.1 [O15539-2] ENST00000530507.5 [O15539-3] O15539 ENST00000367903.7 ENST00000618415.4 [O15539-2] ENST00000531476.1 ENST00000313961.10 [O15539-1] B1APM2 E9PS96 |