Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 14 studies | 25% ± 7% | |
| non-classical monocyte | 13 studies | 27% ± 8% | |
| platelet | 11 studies | 62% ± 21% | |
| conventional dendritic cell | 11 studies | 24% ± 9% | |
| monocyte | 8 studies | 23% ± 8% | |
| megakaryocyte | 6 studies | 80% ± 14% | |
| macrophage | 4 studies | 23% ± 5% | |
| dendritic cell | 4 studies | 28% ± 7% | |
| neutrophil | 4 studies | 23% ± 3% | |
| microglial cell | 3 studies | 19% ± 3% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 23% ± 2% |
Insufficient scRNA-seq data for expression of RGS18 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 466.92 | 578 / 578 | 73% | 2.35 | 841 / 1155 |
| breast | 84% | 60.99 | 385 / 459 | 65% | 1.68 | 730 / 1118 |
| brain | 53% | 49.84 | 1391 / 2642 | 87% | 3.64 | 613 / 705 |
| prostate | 88% | 79.29 | 216 / 245 | 49% | 0.95 | 248 / 502 |
| intestine | 89% | 84.38 | 855 / 966 | 45% | 1.07 | 236 / 527 |
| kidney | 56% | 34.65 | 50 / 89 | 75% | 3.98 | 678 / 901 |
| thymus | 70% | 42.64 | 460 / 653 | 52% | 1.33 | 314 / 605 |
| stomach | 65% | 41.06 | 233 / 359 | 55% | 1.68 | 156 / 286 |
| esophagus | 60% | 33.49 | 863 / 1445 | 56% | 1.26 | 102 / 183 |
| bladder | 76% | 60.76 | 16 / 21 | 39% | 1.02 | 197 / 504 |
| uterus | 68% | 34.48 | 116 / 170 | 39% | 0.83 | 178 / 459 |
| adrenal gland | 81% | 57.94 | 210 / 258 | 25% | 0.49 | 58 / 230 |
| spleen | 100% | 1348.32 | 241 / 241 | 0% | 0 | 0 / 0 |
| liver | 70% | 41.38 | 158 / 226 | 27% | 0.57 | 111 / 406 |
| adipose | 95% | 133.49 | 1145 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 27% | 14.88 | 89 / 328 | 65% | 2.00 | 116 / 178 |
| peripheral blood | 81% | 2791.70 | 755 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 74% | 67.58 | 985 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 28% | 13.96 | 51 / 180 | 45% | 0.95 | 192 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 3.27 | 21 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 1.61 | 30 / 45 |
| heart | 60% | 34.72 | 517 / 861 | 0% | 0 | 0 / 0 |
| skin | 12% | 5.09 | 219 / 1809 | 39% | 1.16 | 185 / 472 |
| muscle | 8% | 2.75 | 61 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.12 | 5 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0008277 | Biological process | regulation of G protein-coupled receptor signaling pathway |
| GO_0009968 | Biological process | negative regulation of signal transduction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005096 | Molecular function | GTPase activator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | RGS18 |
| Protein name | Regulator of G-protein signaling 18 (RGS18) |
| Synonyms | RGS13 |
| Description | FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha. . |
| Accessions | ENST00000367460.4 Q9NS28 |
