RFC4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RFC4 at tissue level.

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_0006271Biological processDNA strand elongation involved in DNA replication
GO_1900264Biological processpositive regulation of DNA-directed DNA polymerase activity
GO_0006281Biological processDNA repair
GO_0006261Biological processDNA-templated DNA replication
GO_0005663Cellular componentDNA replication factor C complex
GO_0005654Cellular componentnucleoplasm
GO_0031390Cellular componentCtf18 RFC-like complex
GO_0031391Cellular componentElg1 RFC-like complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0003689Molecular functionDNA clamp loader activity
GO_0005515Molecular functionprotein binding
GO_0017116Molecular functionsingle-stranded DNA helicase activity
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameRFC4
Protein nameReplication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)
Replication factor C subunit 4
Synonyms
DescriptionFUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.

AccessionsP35249
C9JW34
ENST00000418288.5
ENST00000449502.5
ENST00000427785.5
H7C1P0
C9JGY5
ENST00000417876.1
ENST00000448497.1
C9J8M3
C9JXZ7
ENST00000411792.1
ENST00000392481.6 [P35249-1]
C9JZI1
ENST00000433496.5
F8WE44
ENST00000296273.7 [P35249-1]