Name | Number of supported studies | Average coverage | |
---|---|---|---|
erythroblast | 4 studies | 31% ± 14% | |
natural killer cell | 3 studies | 23% ± 8% | |
CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of RFC4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 862.20 | 170 / 170 | 100% | 74.92 | 457 / 459 |
ovary | 100% | 786.53 | 180 / 180 | 100% | 38.67 | 428 / 430 |
breast | 100% | 527.29 | 459 / 459 | 99% | 29.57 | 1110 / 1118 |
esophagus | 100% | 593.29 | 1444 / 1445 | 98% | 31.97 | 179 / 183 |
stomach | 100% | 492.08 | 359 / 359 | 98% | 24.58 | 279 / 286 |
bladder | 100% | 525.76 | 21 / 21 | 97% | 33.93 | 489 / 504 |
intestine | 100% | 660.64 | 966 / 966 | 97% | 25.96 | 511 / 527 |
brain | 99% | 486.13 | 2617 / 2642 | 98% | 20.91 | 688 / 705 |
skin | 100% | 735.44 | 1808 / 1809 | 96% | 26.39 | 452 / 472 |
lung | 99% | 447.16 | 572 / 578 | 96% | 41.72 | 1114 / 1155 |
pancreas | 99% | 395.82 | 326 / 328 | 93% | 16.29 | 166 / 178 |
prostate | 100% | 531.08 | 245 / 245 | 88% | 10.79 | 440 / 502 |
thymus | 100% | 409.76 | 651 / 653 | 84% | 13.49 | 508 / 605 |
kidney | 100% | 440.89 | 89 / 89 | 79% | 10.22 | 713 / 901 |
liver | 100% | 315.75 | 226 / 226 | 77% | 15.93 | 311 / 406 |
adrenal gland | 98% | 385.10 | 254 / 258 | 41% | 5.58 | 95 / 230 |
lymph node | 0% | 0 | 0 / 0 | 100% | 60.10 | 29 / 29 |
spleen | 100% | 973.26 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 77.81 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.01 | 1 / 1 |
adipose | 100% | 463.82 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 437.47 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 315.66 | 796 / 803 | 0% | 0 | 0 / 0 |
heart | 95% | 323.68 | 819 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 74% | 791.22 | 690 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 43% | 4.69 | 34 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032508 | Biological process | DNA duplex unwinding |
GO_0006271 | Biological process | DNA strand elongation involved in DNA replication |
GO_1900264 | Biological process | positive regulation of DNA-directed DNA polymerase activity |
GO_0006281 | Biological process | DNA repair |
GO_0006261 | Biological process | DNA-templated DNA replication |
GO_0005663 | Cellular component | DNA replication factor C complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0031390 | Cellular component | Ctf18 RFC-like complex |
GO_0031391 | Cellular component | Elg1 RFC-like complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0003689 | Molecular function | DNA clamp loader activity |
GO_0005515 | Molecular function | protein binding |
GO_0017116 | Molecular function | single-stranded DNA helicase activity |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | RFC4 |
Protein name | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) Replication factor C subunit 4 |
Synonyms | |
Description | FUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template. |
Accessions | P35249 C9JW34 ENST00000418288.5 ENST00000449502.5 ENST00000427785.5 H7C1P0 C9JGY5 ENST00000417876.1 ENST00000448497.1 C9J8M3 C9JXZ7 ENST00000411792.1 ENST00000392481.6 [P35249-1] C9JZI1 ENST00000433496.5 F8WE44 ENST00000296273.7 [P35249-1] |