RFC2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RFC2 at tissue level.

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_1900264Biological processpositive regulation of DNA-directed DNA polymerase activity
GO_0006281Biological processDNA repair
GO_0006261Biological processDNA-templated DNA replication
GO_0005663Cellular componentDNA replication factor C complex
GO_0005654Cellular componentnucleoplasm
GO_0031390Cellular componentCtf18 RFC-like complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0019899Molecular functionenzyme binding
GO_0003689Molecular functionDNA clamp loader activity
GO_0005515Molecular functionprotein binding
GO_0017116Molecular functionsingle-stranded DNA helicase activity
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameRFC2
Protein nameReplication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)
Replication factor C subunit 2
Replication factor C (Activator 1) 2, 40kDa
SynonymshCG_18034
DescriptionFUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). .

FUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP. .

AccessionsENST00000494019.5
H7C5P1
ENST00000491206.5
H7C5A0
Q75MT5
H7C5P4
ENST00000463194.1
ENST00000479105.6
H7C5S7
ENST00000493156.6
ENST00000485545.5
ENST00000055077.8 [P35250-1]
H7C5G4
H7C5Q7
H7C596
F8WDC9
F8WC37
ENST00000480432.5
ENST00000497430.1
A0A087WVY3
B5BUD2
ENST00000352131.7 [P35250-2]
ENST00000470266.5
ENST00000621097.4
P35250