Name | Number of supported studies | Average coverage | |
---|---|---|---|
hematopoietic precursor cell | 4 studies | 29% ± 9% | |
natural killer cell | 4 studies | 23% ± 6% | |
conventional dendritic cell | 3 studies | 30% ± 10% | |
epithelial cell | 3 studies | 25% ± 8% | |
dendritic cell | 3 studies | 26% ± 4% | |
transit amplifying cell | 3 studies | 25% ± 3% | |
CD8-positive, alpha-beta T cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of RFC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 886.21 | 180 / 180 | 100% | 52.61 | 430 / 430 |
skin | 100% | 1554.19 | 1809 / 1809 | 100% | 74.96 | 472 / 472 |
stomach | 100% | 827.21 | 359 / 359 | 100% | 48.29 | 286 / 286 |
uterus | 100% | 914.48 | 170 / 170 | 100% | 92.55 | 459 / 459 |
liver | 100% | 872.27 | 226 / 226 | 100% | 37.20 | 405 / 406 |
thymus | 100% | 791.16 | 653 / 653 | 100% | 38.66 | 603 / 605 |
brain | 100% | 743.65 | 2633 / 2642 | 100% | 57.89 | 705 / 705 |
lung | 100% | 966.37 | 577 / 578 | 100% | 60.43 | 1153 / 1155 |
breast | 100% | 1045.44 | 459 / 459 | 100% | 63.77 | 1114 / 1118 |
intestine | 100% | 912.52 | 966 / 966 | 99% | 53.08 | 524 / 527 |
prostate | 100% | 957.74 | 245 / 245 | 99% | 36.00 | 499 / 502 |
esophagus | 100% | 980.49 | 1444 / 1445 | 99% | 54.97 | 182 / 183 |
bladder | 100% | 938.38 | 21 / 21 | 99% | 63.96 | 499 / 504 |
kidney | 100% | 771.12 | 89 / 89 | 99% | 38.28 | 888 / 901 |
pancreas | 98% | 576.41 | 323 / 328 | 99% | 35.79 | 177 / 178 |
adrenal gland | 100% | 729.08 | 258 / 258 | 94% | 25.24 | 217 / 230 |
adipose | 100% | 958.63 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 101.35 | 29 / 29 |
muscle | 100% | 853.33 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1116.57 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 91.73 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 43.70 | 1 / 1 |
blood vessel | 100% | 834.13 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 1649.10 | 924 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 33.92 | 79 / 80 |
heart | 97% | 489.67 | 832 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032508 | Biological process | DNA duplex unwinding |
GO_1900264 | Biological process | positive regulation of DNA-directed DNA polymerase activity |
GO_0006281 | Biological process | DNA repair |
GO_0006261 | Biological process | DNA-templated DNA replication |
GO_0005663 | Cellular component | DNA replication factor C complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0031390 | Cellular component | Ctf18 RFC-like complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0019899 | Molecular function | enzyme binding |
GO_0003689 | Molecular function | DNA clamp loader activity |
GO_0005515 | Molecular function | protein binding |
GO_0017116 | Molecular function | single-stranded DNA helicase activity |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | RFC2 |
Protein name | Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) Replication factor C subunit 2 Replication factor C (Activator 1) 2, 40kDa |
Synonyms | hCG_18034 |
Description | FUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). . FUNCTION: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP. . |
Accessions | ENST00000494019.5 H7C5P1 ENST00000491206.5 H7C5A0 Q75MT5 H7C5P4 ENST00000463194.1 ENST00000479105.6 H7C5S7 ENST00000493156.6 ENST00000485545.5 ENST00000055077.8 [P35250-1] H7C5G4 H7C5Q7 H7C596 F8WDC9 F8WC37 ENST00000480432.5 ENST00000497430.1 A0A087WVY3 B5BUD2 ENST00000352131.7 [P35250-2] ENST00000470266.5 ENST00000621097.4 P35250 |