RBFOX1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
glutamatergic neuron	12 studies	88% ± 19%	Explore
oligodendrocyte	12 studies	45% ± 24%	Explore
astrocyte	11 studies	38% ± 26%	Explore
GABAergic neuron	10 studies	74% ± 28%	Explore
oligodendrocyte precursor cell	10 studies	71% ± 16%	Explore
endothelial cell	9 studies	48% ± 23%	Explore
microglial cell	9 studies	47% ± 23%	Explore
interneuron	6 studies	70% ± 27%	Explore
retinal ganglion cell	6 studies	80% ± 13%	Explore
cardiac muscle cell	6 studies	65% ± 20%	Explore
mesothelial cell	6 studies	52% ± 12%	Explore
neuron	5 studies	62% ± 20%	Explore
amacrine cell	5 studies	73% ± 25%	Explore
granule cell	4 studies	78% ± 24%	Explore
fibroblast	4 studies	27% ± 6%	Explore
Mueller cell	4 studies	32% ± 8%	Explore
macrophage	3 studies	27% ± 10%	Explore
GABAergic interneuron	3 studies	69% ± 35%	Explore
pericyte	3 studies	46% ± 17%	Explore
GABAergic amacrine cell	3 studies	47% ± 10%	Explore
glycinergic amacrine cell	3 studies	74% ± 6%	Explore
smooth muscle cell	3 studies	32% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	60% ± 25%	Explore
heart	4 studies	35% ± 8%	Explore
eye	3 studies	27% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	88%	7237.40	2330 / 2642	62%	5.05	438 / 705
muscle	100%	9206.43	803 / 803	0%	0	0 / 0
heart	88%	2576.17	758 / 861	0%	0	0 / 0
adrenal gland	0%	7.12	1 / 258	45%	1.89	104 / 230
thymus	0%	1.59	1 / 653	14%	0.56	83 / 605
ovary	0%	0	0 / 180	13%	0.44	54 / 430
prostate	4%	41.92	10 / 245	2%	0.03	8 / 502
lymph node	0%	0	0 / 0	3%	0.30	1 / 29
lung	0%	2.94	1 / 578	3%	0.09	34 / 1155
intestine	0%	0.88	1 / 966	3%	0.04	14 / 527
eye	0%	0	0 / 0	3%	0.04	2 / 80
uterus	1%	7.57	1 / 170	2%	0.08	8 / 459
bladder	0%	0	0 / 21	2%	0.05	9 / 504
esophagus	0%	0	0 / 1445	2%	0.03	3 / 183
stomach	0%	0	0 / 359	1%	0.02	4 / 286
pancreas	0%	0	0 / 328	1%	0.04	2 / 178
kidney	0%	0	0 / 89	1%	0.08	10 / 901
breast	0%	1.70	1 / 459	1%	0.01	6 / 1118
liver	0%	0	0 / 226	0%	0.01	2 / 406
skin	0%	2.75	1 / 1809	0%	0.06	2 / 472
blood vessel	0%	8.23	4 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0008380	Biological process	RNA splicing
GO_0050658	Biological process	RNA transport
GO_0006397	Biological process	mRNA processing
GO_0000381	Biological process	regulation of alternative mRNA splicing, via spliceosome
GO_0007399	Biological process	nervous system development
GO_0097165	Cellular component	nuclear stress granule
GO_0005802	Cellular component	trans-Golgi network
GO_0010494	Cellular component	cytoplasmic stress granule
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003729	Molecular function	mRNA binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	RBFOX1
Protein name	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A) (Hexaribonucleotide-binding protein 1) RNA binding protein fox-1 homolog RNA binding fox-1 homolog 1 Fox-1-like RNA-binding protein 1 isoform D RNA binding protein fox-1 homolog 1
Synonyms	hCG_1811870 A2BP1 HRNBP1 A2BP FOX1
Description	FUNCTION: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. . FUNCTION: RNA-binding protein that regulates alternative splicing events. .
Accessions	A0A087X2B1 X5D7T5 A0A804HKG7 ENST00000552089.5 ENST00000550418.6 [Q9NWB1-1] ENST00000570626.2 A0A286YFF2 F8VR27 ENST00000355637.9 [Q9NWB1-5] ENST00000585867.2 ENST00000547338.5 [Q9NWB1-1] F8VZY7 I3L1D4 A0A6Q8PFM4 A0A286YEU2 ENST00000674626.1 B7Z1U7 ENST00000553186.5 [Q9NWB1-3] F5H0M1 X5DP44 ENST00000422070.8 X5DNY3 ENST00000547605.5 ENST00000675459.1 ENST00000551752.5 ENST00000547372.5 H3BM62 A0A994J531 ENST00000674792.1 A0A6Q8PHA3 ENST00000683326.1 ENST00000567470.1 ENST00000641259.1 F8VZG9 ENST00000676218.1 ENST00000682918.1 A0A6Q8PH77 ENST00000535565.6 ENST00000620507.4 F8VRS4 ENST00000675562.1 ENST00000436368.6 [Q9NWB1-4] A0A6Q8PGE0 A0A804HJM2 ENST00000311745.9 [Q9NWB1-2] Q9NWB1 ENST00000675842.1 [Q9NWB1-1] ENST00000705321.1 ENST00000675653.1 [Q9NWB1-1]

RBFOX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review