RASGRP4 | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	7 studies	26% ± 7%	Explore
non-classical monocyte	5 studies	24% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of RASGRP4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1378.84	578 / 578	71%	1.87	815 / 1155
breast	90%	249.63	413 / 459	70%	1.51	781 / 1118
stomach	79%	187.56	282 / 359	61%	1.42	175 / 286
bladder	100%	294.81	21 / 21	39%	0.92	198 / 504
intestine	94%	241.97	912 / 966	44%	0.98	230 / 527
esophagus	80%	204.70	1162 / 1445	52%	1.08	96 / 183
kidney	53%	110.79	47 / 89	75%	2.26	673 / 901
adrenal gland	93%	241.78	240 / 258	28%	0.52	64 / 230
brain	31%	49.22	818 / 2642	90%	3.56	631 / 705
uterus	83%	159.97	141 / 170	35%	0.68	160 / 459
skin	57%	101.74	1026 / 1809	59%	1.50	277 / 472
prostate	82%	165.69	202 / 245	32%	0.48	161 / 502
ovary	37%	61.24	66 / 180	67%	1.82	288 / 430
spleen	100%	3998.44	241 / 241	0%	0	0 / 0
adipose	99%	571.67	1196 / 1204	0%	0	0 / 0
peripheral blood	93%	13429.29	862 / 929	0%	0	0 / 0
thymus	53%	78.56	345 / 653	40%	0.76	240 / 605
pancreas	24%	36.40	78 / 328	68%	1.75	121 / 178
liver	58%	111.09	132 / 226	20%	0.37	83 / 406
blood vessel	73%	196.23	973 / 1335	0%	0	0 / 0
heart	68%	125.94	589 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	3.94	18 / 29
tonsil	0%	0	0 / 0	49%	0.84	22 / 45
muscle	40%	54.58	323 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	30%	0.47	24 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0140367	Biological process	antibacterial innate immune response
GO_0002717	Biological process	positive regulation of natural killer cell mediated immunity
GO_0007265	Biological process	Ras protein signal transduction
GO_0030099	Biological process	myeloid cell differentiation
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0005509	Molecular function	calcium ion binding
GO_0019992	Molecular function	diacylglycerol binding

Gene name	RASGRP4
Protein name	RAS guanyl releasing protein 4 variant 9 RAS guanyl-releasing protein 4
Synonyms
Description	FUNCTION: Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast cells differentiation. .
Accessions	ENST00000615439.5 [Q8TDF6-1] Q8TDF6 ENST00000586305.5 [Q8TDF6-2] ENST00000454404.6 [Q8TDF6-8] ENST00000589358.5 [Q8TDF6-1] C0LTP6 ENST00000587753.5 [Q8TDF6-9] ENST00000617966.4 [Q8TDF6-7] ENST00000622174.4 [Q8TDF6-6] ENST00000614135.4 [Q8TDF6-5] ENST00000587738.2 [Q8TDF6-1] ENST00000589474.5 [Q8TDF6-2]

RASGRP4 report