RAP2C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0061097Biological processregulation of protein tyrosine kinase activity
GO_0030033Biological processmicrovillus assembly
GO_0032486Biological processRap protein signal transduction
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0090557Biological processestablishment of endothelial intestinal barrier
GO_0031954Biological processpositive regulation of protein autophosphorylation
GO_0030336Biological processnegative regulation of cell migration
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0055038Cellular componentrecycling endosome membrane
GO_0044291Cellular componentcell-cell contact zone
GO_0005829Cellular componentcytosol
GO_0070821Cellular componenttertiary granule membrane
GO_0005737Cellular componentcytoplasm
GO_0005923Cellular componentbicellular tight junction
GO_0019003Molecular functionGDP binding
GO_0003925Molecular functionG protein activity
GO_0005525Molecular functionGTP binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAP2C
Protein nameRas-related protein Rap-2c (EC 3.6.5.2)
RAP2C, member of RAS oncogene family
SynonymshCG_2043125
DescriptionFUNCTION: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. .

AccessionsENST00000342983.6
A0A087X2C3
ENST00000370874.2
ENST00000620646.4
Q9Y3L5