RAB43 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of RAB43 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	879.24	180 / 180	86%	2.73	369 / 430
esophagus	100%	493.58	1443 / 1445	78%	1.73	143 / 183
stomach	100%	600.72	359 / 359	77%	1.90	219 / 286
liver	100%	1641.54	226 / 226	73%	1.65	297 / 406
prostate	100%	924.06	245 / 245	65%	1.35	326 / 502
intestine	100%	615.15	966 / 966	65%	1.29	341 / 527
skin	99%	521.00	1798 / 1809	65%	1.24	305 / 472
lung	100%	1314.90	578 / 578	55%	1.01	635 / 1155
thymus	100%	1076.51	653 / 653	50%	0.90	301 / 605
pancreas	99%	463.12	324 / 328	49%	0.74	88 / 178
bladder	100%	639.48	21 / 21	46%	0.81	233 / 504
kidney	100%	831.79	89 / 89	35%	0.54	319 / 901
breast	100%	779.29	459 / 459	31%	0.49	346 / 1118
uterus	100%	687.45	170 / 170	27%	0.42	124 / 459
adrenal gland	100%	778.25	258 / 258	3%	0.07	7 / 230
adipose	100%	740.19	1204 / 1204	0%	0	0 / 0
spleen	100%	1059.63	241 / 241	0%	0	0 / 0
blood vessel	100%	850.21	1334 / 1335	0%	0	0 / 0
peripheral blood	100%	2072.23	926 / 929	0%	0	0 / 0
brain	94%	337.83	2474 / 2642	5%	0.07	38 / 705
heart	90%	262.08	778 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	45%	0.93	13 / 29
tonsil	0%	0	0 / 0	29%	0.53	13 / 45
muscle	29%	50.21	230 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.03	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007030	Biological process	Golgi organization
GO_0006886	Biological process	intracellular protein transport
GO_0035526	Biological process	retrograde transport, plasma membrane to Golgi
GO_0090382	Biological process	phagosome maturation
GO_0019068	Biological process	virion assembly
GO_0000045	Biological process	autophagosome assembly
GO_0071346	Biological process	cellular response to type II interferon
GO_0032588	Cellular component	trans-Golgi network membrane
GO_0070062	Cellular component	extracellular exosome
GO_0045335	Cellular component	phagocytic vesicle
GO_0005794	Cellular component	Golgi apparatus
GO_0012505	Cellular component	endomembrane system
GO_0030670	Cellular component	phagocytic vesicle membrane
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0003924	Molecular function	GTPase activity

Gene name	RAB43
Protein name	Ras-related protein Rab-43 (Ras-related protein Rab-41) Ras-related protein Rab-10
Synonyms	RAB41
Description	FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. .
Accessions	ENST00000393307.5 [Q86YS6-1] ENST00000393308.5 [Q86YS6-1] ENST00000476465.5 [Q86YS6-2] Q86YS6 ENST00000393305.5 [Q86YS6-1] C9JFM7 ENST00000457077.1 ENST00000315150.10 [Q86YS6-1] ENST00000615093.1 [Q86YS6-2] ENST00000393304.5 [Q86YS6-1]

RAB43 report