PYCR2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006561Biological processproline biosynthetic process
GO_0034599Biological processcellular response to oxidative stress
GO_0055129Biological processL-proline biosynthetic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding
GO_0004735Molecular functionpyrroline-5-carboxylate reductase activity

IV. Literature review

[source]
Gene namePYCR2
Protein namePyrroline-5-carboxylate reductase (EC 1.5.1.2)
Pyrroline-5-carboxylate reductase 2 (EC 1.5.1.2)
Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2)
Pyrroline-5-carboxylate reductase family member 2 isoform 2
Pyrroline-5-carboxylate reductase 2
SynonymshCG_32783
DescriptionFUNCTION: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH . Involved in cellular response to oxidative stress . .

AccessionsA0A087WX69
A0A087WZF0
ENST00000489681.5
B3KMB7
ENST00000612039.4
A0A0S2Z5U6
A0A087WTV6
ENST00000472798.2
ENST00000343818.11
A0A0S2Z578
Q96C36