Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 22% ± 7% | |
fibroblast | 10 studies | 22% ± 7% | |
epithelial cell | 9 studies | 38% ± 18% | |
ciliated cell | 7 studies | 33% ± 13% | |
basal cell | 7 studies | 31% ± 15% | |
oligodendrocyte | 7 studies | 26% ± 8% | |
endothelial cell of lymphatic vessel | 6 studies | 22% ± 5% | |
astrocyte | 6 studies | 20% ± 5% | |
kidney loop of Henle epithelial cell | 5 studies | 21% ± 3% | |
neuron | 5 studies | 34% ± 14% | |
glutamatergic neuron | 5 studies | 36% ± 14% | |
pancreatic A cell | 4 studies | 42% ± 12% | |
club cell | 4 studies | 20% ± 4% | |
hepatocyte | 4 studies | 34% ± 24% | |
GABAergic neuron | 4 studies | 37% ± 13% | |
oligodendrocyte precursor cell | 4 studies | 22% ± 4% | |
connective tissue cell | 4 studies | 24% ± 10% | |
interneuron | 4 studies | 31% ± 16% | |
respiratory goblet cell | 3 studies | 27% ± 16% | |
type B pancreatic cell | 3 studies | 45% ± 4% | |
non-classical monocyte | 3 studies | 18% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 0% | |
conventional dendritic cell | 3 studies | 20% ± 4% | |
retinal ganglion cell | 3 studies | 45% ± 24% | |
myofibroblast cell | 3 studies | 20% ± 3% | |
macrophage | 3 studies | 20% ± 4% | |
dendritic cell | 3 studies | 26% ± 10% | |
natural killer cell | 3 studies | 17% ± 2% | |
abnormal cell | 3 studies | 21% ± 5% | |
goblet cell | 3 studies | 23% ± 5% | |
endothelial cell of vascular tree | 3 studies | 21% ± 6% | |
pericyte | 3 studies | 21% ± 6% | |
secretory cell | 3 studies | 31% ± 16% | |
plasmacytoid dendritic cell | 3 studies | 21% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 762.31 | 1445 / 1445 | 100% | 15.37 | 183 / 183 |
ovary | 100% | 539.61 | 180 / 180 | 100% | 18.36 | 430 / 430 |
prostate | 100% | 887.26 | 245 / 245 | 100% | 27.97 | 502 / 502 |
stomach | 100% | 751.11 | 359 / 359 | 100% | 16.41 | 286 / 286 |
uterus | 100% | 638.72 | 170 / 170 | 100% | 19.60 | 459 / 459 |
kidney | 100% | 1144.63 | 89 / 89 | 100% | 16.00 | 900 / 901 |
brain | 100% | 1066.60 | 2638 / 2642 | 100% | 17.28 | 705 / 705 |
intestine | 100% | 667.13 | 966 / 966 | 100% | 18.41 | 526 / 527 |
bladder | 100% | 783.67 | 21 / 21 | 100% | 19.51 | 503 / 504 |
liver | 100% | 1406.08 | 226 / 226 | 100% | 15.88 | 405 / 406 |
thymus | 100% | 833.91 | 653 / 653 | 100% | 20.33 | 603 / 605 |
breast | 100% | 624.67 | 459 / 459 | 100% | 19.61 | 1114 / 1118 |
adrenal gland | 100% | 2224.31 | 258 / 258 | 100% | 38.24 | 229 / 230 |
lung | 99% | 530.65 | 574 / 578 | 100% | 21.22 | 1155 / 1155 |
pancreas | 99% | 325.12 | 325 / 328 | 99% | 18.49 | 176 / 178 |
skin | 100% | 706.99 | 1805 / 1809 | 95% | 12.68 | 449 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.01 | 29 / 29 |
muscle | 100% | 1035.36 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 451.71 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 12.86 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.71 | 1 / 1 |
blood vessel | 100% | 819.42 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 587.31 | 1202 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 574.23 | 848 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 14.66 | 78 / 80 |
peripheral blood | 27% | 96.64 | 247 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006729 | Biological process | tetrahydrobiopterin biosynthetic process |
GO_0006520 | Biological process | amino acid metabolic process |
GO_0007417 | Biological process | central nervous system development |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005739 | Cellular component | mitochondrion |
GO_0003874 | Molecular function | 6-pyruvoyltetrahydropterin synthase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | PTS |
Protein name | 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) 6-pyruvoyltetrahydropterin synthase (EC 4.2.3.12) 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) |
Synonyms | PTPS |
Description | FUNCTION: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. . FUNCTION: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. . |
Accessions | ENST00000280362.8 E9PKY8 E9PNN3 E9PJM0 ENST00000524931.1 ENST00000528679.5 ENST00000531673.5 Q03393 ENST00000525803.1 |