PTRH1 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	9 studies	40% ± 14%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PTRH1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	98%	274.61	177 / 180	5%	0.07	20 / 430
skin	100%	696.44	1808 / 1809	1%	0.02	7 / 472
adrenal gland	100%	724.95	258 / 258	0%	0.00	1 / 230
bladder	100%	393.52	21 / 21	0%	0	0 / 504
kidney	100%	695.31	89 / 89	0%	0	0 / 901
prostate	100%	461.24	245 / 245	0%	0	0 / 502
spleen	100%	391.88	241 / 241	0%	0	0 / 0
stomach	100%	356.94	359 / 359	0%	0	0 / 286
thymus	100%	694.60	653 / 653	0%	0	0 / 605
uterus	100%	546.84	170 / 170	0%	0	0 / 459
adipose	100%	453.79	1203 / 1204	0%	0	0 / 0
lung	100%	1054.22	577 / 578	0%	0.00	1 / 1155
intestine	99%	318.01	961 / 966	0%	0.01	2 / 527
breast	100%	500.87	458 / 459	0%	0	0 / 1118
brain	99%	553.79	2628 / 2642	0%	0.01	2 / 705
esophagus	100%	345.58	1440 / 1445	0%	0	0 / 183
pancreas	99%	358.01	326 / 328	0%	0	0 / 178
blood vessel	99%	312.74	1322 / 1335	0%	0	0 / 0
liver	98%	285.25	222 / 226	0%	0	0 / 406
muscle	97%	360.45	777 / 803	0%	0	0 / 0
heart	96%	326.26	825 / 861	0%	0	0 / 0
peripheral blood	66%	152.25	612 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	PTRH1
Protein name	Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29) peptidyl-tRNA hydrolase (EC 3.1.1.29) Peptidyl-tRNA hydrolase 1 homolog
Synonyms	C9orf115
Description	FUNCTION: Peptidyl-tRNA hydrolase that cleaves nascent chains-tRNAs that are not stably fixed in the P-site of 60S ribosome-nascent chain complexes . Acts downstream of the ribosome-associated quality control (RQC) pathway to release non-ubiquitinated nascent chains from 60S and 80S ribosome-nascent chain complexes . Does not act on ubiquitinated nascent chains, which are cleaved by ANKZF1 for degradation . .
Accessions	ENST00000543175.5 ENST00000423807.5 ENST00000414832.2 A0A096LP34 A0A096LPA3 ENST00000641641.1 A0A286YER0 A0A096LP22 ENST00000419060.5 A0A286YF52 ENST00000335223.5 C9J7Z1 ENST00000416214.1 Q86Y79 ENST00000456267.5

GO_0072344	Biological process	rescue of stalled ribosome
GO_0004045	Molecular function	aminoacyl-tRNA hydrolase activity
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

PTRH1 report