Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 11 studies | 54% ± 23% | |
| GABAergic neuron | 8 studies | 43% ± 25% | |
| interneuron | 5 studies | 44% ± 21% | |
| retina horizontal cell | 4 studies | 46% ± 10% | |
| neuron | 3 studies | 26% ± 5% | |
| endothelial cell | 3 studies | 29% ± 10% | |
| GABAergic amacrine cell | 3 studies | 31% ± 10% | |
| OFF-bipolar cell | 3 studies | 54% ± 26% | |
| amacrine cell | 3 studies | 39% ± 20% | |
| granule cell | 3 studies | 48% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 10 studies | 36% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 90% | 265.26 | 873 / 966 | 86% | 6.62 | 453 / 527 |
| brain | 91% | 869.95 | 2404 / 2642 | 52% | 2.47 | 367 / 705 |
| stomach | 62% | 72.61 | 224 / 359 | 79% | 5.92 | 225 / 286 |
| bladder | 57% | 259.81 | 12 / 21 | 68% | 9.89 | 343 / 504 |
| uterus | 83% | 360.82 | 141 / 170 | 31% | 3.33 | 141 / 459 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.62 | 1 / 1 |
| thymus | 53% | 56.07 | 344 / 653 | 47% | 1.06 | 283 / 605 |
| pancreas | 1% | 0.33 | 2 / 328 | 85% | 8.50 | 151 / 178 |
| lung | 39% | 35.98 | 224 / 578 | 36% | 1.88 | 411 / 1155 |
| esophagus | 25% | 21.37 | 355 / 1445 | 47% | 2.47 | 86 / 183 |
| spleen | 70% | 73.32 | 168 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 21% | 45.24 | 55 / 258 | 45% | 4.16 | 103 / 230 |
| kidney | 8% | 5.36 | 7 / 89 | 28% | 0.76 | 256 / 901 |
| skin | 8% | 6.04 | 139 / 1809 | 28% | 1.21 | 133 / 472 |
| ovary | 4% | 2.87 | 8 / 180 | 28% | 1.46 | 122 / 430 |
| blood vessel | 32% | 29.33 | 432 / 1335 | 0% | 0 | 0 / 0 |
| heart | 27% | 21.04 | 233 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 26% | 1.83 | 21 / 80 |
| breast | 13% | 10.02 | 58 / 459 | 13% | 0.46 | 148 / 1118 |
| prostate | 7% | 5.49 | 17 / 245 | 15% | 1.60 | 75 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 0.43 | 7 / 45 |
| adipose | 12% | 7.90 | 143 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.59 | 2 / 29 |
| liver | 0% | 0 | 0 / 226 | 4% | 0.19 | 18 / 406 |
| muscle | 4% | 2.72 | 34 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 0.39 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0038128 | Biological process | ERBB2 signaling pathway |
| GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
| GO_0010633 | Biological process | negative regulation of epithelial cell migration |
| GO_1903385 | Biological process | regulation of homophilic cell adhesion |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0030054 | Cellular component | cell junction |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005001 | Molecular function | transmembrane receptor protein tyrosine phosphatase activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| Gene name | PTPRR |
| Protein name | protein-tyrosine-phosphatase (EC 3.1.3.48) Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) |
| Synonyms | PTPRQ ECPTP |
| Description | FUNCTION: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). . |
| Accessions | ENST00000378778.5 [Q15256-4] ENST00000550661.1 Q05B41 F8VVE9 ENST00000551219.5 ENST00000440835.6 [Q15256-3] Q2TAJ3 Q0VD90 ENST00000283228.7 [Q15256-1] ENST00000342084.8 [Q15256-5] Q569H9 Q15256 ENST00000549308.5 [Q15256-3] F8VU63 |
