I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 8 studies | 38% ± 24% | |
| GABAergic neuron | 6 studies | 38% ± 21% | |
| neuron | 3 studies | 23% ± 3% | |
| interneuron | 3 studies | 27% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 8 studies | 38% ± 24% | |
| GABAergic neuron | 6 studies | 38% ± 21% | |
| neuron | 3 studies | 23% ± 3% | |
| interneuron | 3 studies | 27% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 35% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 93% | 11134.63 | 2462 / 2642 | 83% | 13.41 | 584 / 705 |
| heart | 70% | 488.21 | 601 / 861 | 0% | 0 | 0 / 0 |
| ovary | 53% | 234.99 | 95 / 180 | 12% | 0.32 | 51 / 430 |
| esophagus | 39% | 173.41 | 563 / 1445 | 4% | 0.06 | 8 / 183 |
| prostate | 20% | 86.93 | 50 / 245 | 15% | 0.26 | 74 / 502 |
| pancreas | 0% | 0 | 0 / 328 | 33% | 0.74 | 58 / 178 |
| breast | 29% | 119.54 | 133 / 459 | 2% | 0.04 | 24 / 1118 |
| bladder | 29% | 87.38 | 6 / 21 | 2% | 0.04 | 12 / 504 |
| lung | 24% | 135.11 | 136 / 578 | 4% | 0.10 | 50 / 1155 |
| stomach | 19% | 69.47 | 68 / 359 | 9% | 0.18 | 25 / 286 |
| thymus | 11% | 38.62 | 75 / 653 | 9% | 0.14 | 55 / 605 |
| uterus | 11% | 44.10 | 19 / 170 | 8% | 0.28 | 37 / 459 |
| blood vessel | 19% | 77.07 | 250 / 1335 | 0% | 0 | 0 / 0 |
| intestine | 14% | 41.64 | 136 / 966 | 4% | 0.07 | 19 / 527 |
| adipose | 16% | 55.31 | 189 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 5% | 15.81 | 13 / 258 | 10% | 0.35 | 22 / 230 |
| kidney | 4% | 15.28 | 4 / 89 | 7% | 0.12 | 66 / 901 |
| skin | 3% | 8.09 | 51 / 1809 | 1% | 0.03 | 7 / 472 |
| spleen | 4% | 14.12 | 10 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
| muscle | 1% | 5.48 | 12 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| liver | 1% | 2.21 | 2 / 226 | 0% | 0 | 0 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0030054 | Cellular component | cell junction |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001784 | Molecular function | phosphotyrosine residue binding |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| Gene name | PTPN5 |
| Protein name | protein-tyrosine-phosphatase (EC 3.1.3.48) Alternative protein PTPN5 Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP) |
| Synonyms | |
| Description | FUNCTION: May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. . |
| Accessions | Q86TL6 ENST00000477854.5 ENST00000396166.7 P54829 E9PLZ4 ENST00000396170.5 [P54829-2] A8MXF1 Q86TL3 ENST00000396168.1 [P54829-3] L8E916 ENST00000358540.7 [P54829-1] |
