PTPN18 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901185Biological processnegative regulation of ERBB signaling pathway
GO_0006470Biological processprotein dephosphorylation
GO_0001825Biological processblastocyst formation
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004726Molecular functionnon-membrane spanning protein tyrosine phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePTPN18
Protein nameTyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase)
protein-tyrosine-phosphatase (EC 3.1.3.48)
Protein tyrosine phosphatase non-receptor type 18
SynonymsBDP1
DescriptionFUNCTION: Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.

AccessionsF8WBM9
ENST00000347849.7 [Q99952-2]
ENST00000175756.10 [Q99952-1]
ENST00000409022.2
E7EMB8
Q99952
ENST00000428843.5