Name | Number of supported studies | Average coverage | |
---|---|---|---|
non-classical monocyte | 19 studies | 32% ± 15% | |
natural killer cell | 18 studies | 20% ± 5% | |
B cell | 14 studies | 22% ± 8% | |
classical monocyte | 13 studies | 29% ± 12% | |
macrophage | 13 studies | 25% ± 7% | |
platelet | 11 studies | 38% ± 12% | |
monocyte | 9 studies | 24% ± 6% | |
memory B cell | 8 studies | 20% ± 5% | |
CD16-positive, CD56-dim natural killer cell, human | 8 studies | 26% ± 8% | |
conventional dendritic cell | 8 studies | 29% ± 14% | |
myeloid cell | 7 studies | 25% ± 9% | |
dendritic cell | 7 studies | 28% ± 17% | |
epithelial cell | 6 studies | 27% ± 9% | |
microglial cell | 6 studies | 28% ± 9% | |
plasmacytoid dendritic cell | 5 studies | 26% ± 6% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 3% | |
endothelial cell | 4 studies | 19% ± 2% | |
megakaryocyte | 4 studies | 34% ± 15% | |
ciliated cell | 4 studies | 23% ± 3% | |
brush cell | 4 studies | 75% ± 16% | |
abnormal cell | 4 studies | 22% ± 7% | |
CD8-positive, alpha-beta T cell | 3 studies | 22% ± 5% | |
mature NK T cell | 3 studies | 21% ± 6% | |
germinal center B cell | 3 studies | 29% ± 4% | |
GABAergic neuron | 3 studies | 29% ± 4% | |
glutamatergic neuron | 3 studies | 37% ± 9% | |
goblet cell | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3691.59 | 1445 / 1445 | 100% | 42.06 | 183 / 183 |
intestine | 100% | 6038.62 | 966 / 966 | 100% | 51.77 | 527 / 527 |
pancreas | 100% | 3792.45 | 328 / 328 | 100% | 60.58 | 178 / 178 |
prostate | 100% | 6977.26 | 245 / 245 | 100% | 88.68 | 502 / 502 |
stomach | 100% | 4069.11 | 359 / 359 | 100% | 49.11 | 286 / 286 |
thymus | 100% | 4623.37 | 653 / 653 | 100% | 34.72 | 605 / 605 |
skin | 100% | 2614.19 | 1807 / 1809 | 100% | 46.15 | 472 / 472 |
bladder | 100% | 3958.76 | 21 / 21 | 100% | 42.57 | 503 / 504 |
uterus | 100% | 3984.36 | 170 / 170 | 100% | 42.91 | 458 / 459 |
ovary | 100% | 2593.46 | 180 / 180 | 100% | 49.16 | 429 / 430 |
breast | 100% | 4950.04 | 459 / 459 | 100% | 59.70 | 1114 / 1118 |
lung | 100% | 4958.92 | 577 / 578 | 100% | 41.14 | 1152 / 1155 |
liver | 100% | 3582.16 | 226 / 226 | 100% | 25.06 | 404 / 406 |
brain | 99% | 3532.03 | 2609 / 2642 | 100% | 32.38 | 705 / 705 |
kidney | 100% | 4515.99 | 89 / 89 | 97% | 47.59 | 876 / 901 |
adrenal gland | 99% | 2458.83 | 256 / 258 | 86% | 22.01 | 197 / 230 |
adipose | 100% | 4846.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 37.62 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 155.89 | 29 / 29 |
spleen | 100% | 12800.27 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.90 | 1 / 1 |
peripheral blood | 100% | 7529.86 | 927 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3561.80 | 1331 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 36.02 | 44 / 45 |
heart | 96% | 1796.49 | 829 / 861 | 0% | 0 | 0 / 0 |
muscle | 57% | 692.13 | 456 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1901185 | Biological process | negative regulation of ERBB signaling pathway |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0001825 | Biological process | blastocyst formation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004726 | Molecular function | non-membrane spanning protein tyrosine phosphatase activity |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PTPN18 |
Protein name | Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase) protein-tyrosine-phosphatase (EC 3.1.3.48) Protein tyrosine phosphatase non-receptor type 18 |
Synonyms | BDP1 |
Description | FUNCTION: Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. |
Accessions | F8WBM9 ENST00000347849.7 [Q99952-2] ENST00000175756.10 [Q99952-1] ENST00000409022.2 E7EMB8 Q99952 ENST00000428843.5 |