I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| myofibroblast cell | 3 studies | 26% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| myofibroblast cell | 3 studies | 26% ± 4% |
Insufficient scRNA-seq data for expression of PTGER1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 99% | 162.88 | 356 / 359 | 67% | 4.18 | 192 / 286 |
| adrenal gland | 100% | 90.33 | 258 / 258 | 63% | 3.98 | 145 / 230 |
| esophagus | 94% | 57.24 | 1358 / 1445 | 65% | 2.40 | 119 / 183 |
| lung | 98% | 162.21 | 569 / 578 | 53% | 2.30 | 616 / 1155 |
| bladder | 95% | 73.95 | 20 / 21 | 40% | 1.24 | 201 / 504 |
| intestine | 82% | 44.13 | 795 / 966 | 48% | 2.02 | 254 / 527 |
| uterus | 78% | 36.82 | 133 / 170 | 45% | 2.05 | 205 / 459 |
| kidney | 100% | 687.98 | 89 / 89 | 15% | 0.54 | 137 / 901 |
| ovary | 18% | 4.81 | 33 / 180 | 92% | 13.37 | 394 / 430 |
| thymus | 77% | 42.51 | 505 / 653 | 31% | 0.75 | 188 / 605 |
| prostate | 86% | 51.67 | 210 / 245 | 20% | 0.35 | 98 / 502 |
| pancreas | 44% | 10.27 | 145 / 328 | 59% | 1.61 | 105 / 178 |
| spleen | 100% | 423.46 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.69 | 1 / 1 |
| brain | 75% | 25.99 | 1977 / 2642 | 13% | 0.22 | 89 / 705 |
| breast | 80% | 29.57 | 365 / 459 | 8% | 0.17 | 88 / 1118 |
| adipose | 83% | 45.08 | 1005 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 79% | 4.02 | 63 / 80 |
| liver | 52% | 10.55 | 118 / 226 | 24% | 0.71 | 99 / 406 |
| skin | 43% | 12.28 | 783 / 1809 | 26% | 0.84 | 125 / 472 |
| blood vessel | 61% | 26.73 | 811 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 0.76 | 10 / 45 |
| heart | 11% | 2.33 | 92 / 861 | 0% | 0 | 0 / 0 |
| muscle | 10% | 1.77 | 79 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 4% | 0.69 | 39 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007191 | Biological process | adenylate cyclase-activating dopamine receptor signaling pathway |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0006954 | Biological process | inflammatory response |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004957 | Molecular function | prostaglandin E receptor activity |
| GO_0031748 | Molecular function | D1 dopamine receptor binding |
| Gene name | PTGER1 |
| Protein name | PTGER1 protein Prostaglandin E2 receptor EP1 subtype (PGE receptor EP1 subtype) (PGE2 receptor EP1 subtype) (Prostanoid EP1 receptor) |
| Synonyms | |
| Description | FUNCTION: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
| Accessions | Q05C32 P34995 ENST00000292513.4 |
