PSD4 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	5 studies	22% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	20% ± 4%	Explore
gamma-delta T cell	4 studies	22% ± 5%	Explore
natural killer cell	4 studies	18% ± 1%	Explore
CD8-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	19% ± 4%	Explore
lymphocyte	3 studies	17% ± 2%	Explore
hepatocyte	3 studies	39% ± 19%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PSD4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	6853.86	653 / 653	100%	26.54	605 / 605
pancreas	100%	3602.78	327 / 328	99%	21.84	177 / 178
lung	99%	3275.54	574 / 578	99%	17.65	1142 / 1155
liver	100%	7077.68	226 / 226	96%	14.36	391 / 406
prostate	91%	5712.27	224 / 245	100%	35.84	502 / 502
kidney	100%	2456.30	89 / 89	90%	10.20	811 / 901
stomach	78%	4308.95	281 / 359	98%	18.89	281 / 286
breast	65%	2582.22	298 / 459	99%	25.04	1109 / 1118
intestine	54%	3419.08	521 / 966	100%	19.35	526 / 527
bladder	52%	1687.62	11 / 21	97%	16.08	488 / 504
adrenal gland	100%	6825.97	258 / 258	49%	5.62	113 / 230
esophagus	42%	1925.89	603 / 1445	100%	21.83	183 / 183
skin	73%	3542.55	1317 / 1809	46%	5.02	216 / 472
uterus	14%	202.84	24 / 170	90%	14.79	414 / 459
ovary	4%	47.50	8 / 180	99%	15.82	425 / 430
lymph node	0%	0	0 / 0	100%	42.90	29 / 29
spleen	100%	11707.47	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.93	45 / 45
ureter	0%	0	0 / 0	100%	11.84	1 / 1
peripheral blood	100%	13589.00	927 / 929	0%	0	0 / 0
brain	30%	312.76	780 / 2642	29%	1.95	202 / 705
adipose	42%	560.13	510 / 1204	0%	0	0 / 0
blood vessel	12%	180.60	159 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	11%	0.63	9 / 80
heart	3%	35.35	27 / 861	0%	0	0 / 0
muscle	0%	1.22	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0032012	Biological process	regulation of ARF protein signal transduction
GO_0032587	Cellular component	ruffle membrane
GO_0032154	Cellular component	cleavage furrow
GO_0016020	Cellular component	membrane
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0005543	Molecular function	phospholipid binding

Gene name	PSD4
Protein name	Pleckstrin and Sec7 domain containing 4 PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein)
Synonyms	EFA6B TIC
Description	FUNCTION: Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. .
Accessions	ENST00000245796.11 [Q8NDX1-1] ENST00000409656.5 B8ZZZ5 Q8NDX1 H7BZ06 ENST00000409378.1 ENST00000441564.7 [Q8NDX1-2]

PSD4 report