PRSS8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010765Biological processpositive regulation of sodium ion transport
GO_0006508Biological processproteolysis
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0008236Molecular functionserine-type peptidase activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene namePRSS8
Protein nameProstasin (EC 3.4.21.-) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain]
Serine protease 8
Synonyms
DescriptionFUNCTION: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). .

AccessionsH3BUJ8
ENST00000567797.1
H3BVC8
ENST00000317508.11 [Q16651-1]
ENST00000567531.5
Q16651
ENST00000568261.5 [Q16651-2]