Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 14 studies | 39% ± 21% | |
| type I pneumocyte | 10 studies | 44% ± 18% | |
| type II pneumocyte | 7 studies | 31% ± 17% | |
| enterocyte | 7 studies | 35% ± 11% | |
| goblet cell | 6 studies | 24% ± 4% | |
| basal cell | 6 studies | 35% ± 12% | |
| squamous epithelial cell | 4 studies | 58% ± 13% | |
| club cell | 4 studies | 29% ± 13% | |
| respiratory goblet cell | 3 studies | 27% ± 15% | |
| kidney loop of Henle epithelial cell | 3 studies | 32% ± 16% | |
| extravillous trophoblast | 3 studies | 81% ± 4% | |
| placental villous trophoblast | 3 studies | 41% ± 7% | |
| progenitor cell | 3 studies | 37% ± 18% | |
| secretory cell | 3 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 3100.20 | 648 / 653 | 93% | 108.21 | 565 / 605 |
| pancreas | 100% | 3591.86 | 327 / 328 | 90% | 136.54 | 160 / 178 |
| lung | 91% | 3335.86 | 524 / 578 | 91% | 136.73 | 1051 / 1155 |
| prostate | 83% | 2282.82 | 203 / 245 | 98% | 239.32 | 492 / 502 |
| stomach | 76% | 6459.08 | 274 / 359 | 95% | 189.10 | 272 / 286 |
| kidney | 100% | 3974.64 | 89 / 89 | 57% | 41.81 | 514 / 901 |
| breast | 53% | 1508.93 | 241 / 459 | 96% | 190.78 | 1076 / 1118 |
| intestine | 46% | 5009.53 | 442 / 966 | 96% | 210.02 | 508 / 527 |
| esophagus | 39% | 2508.11 | 566 / 1445 | 87% | 110.96 | 159 / 183 |
| ovary | 1% | 3.72 | 1 / 180 | 97% | 139.48 | 419 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 98.63 | 44 / 45 |
| bladder | 19% | 172.62 | 4 / 21 | 74% | 105.27 | 372 / 504 |
| uterus | 5% | 118.25 | 9 / 170 | 83% | 115.03 | 381 / 459 |
| skin | 72% | 4454.16 | 1301 / 1809 | 2% | 1.78 | 11 / 472 |
| liver | 50% | 574.92 | 113 / 226 | 19% | 18.41 | 77 / 406 |
| adrenal gland | 0% | 2.82 | 1 / 258 | 3% | 3.15 | 7 / 230 |
| adipose | 1% | 10.49 | 7 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 3.23 | 2 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 2.14 | 2 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 2.98 | 2 / 1335 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0.09 | 1 / 705 |
| peripheral blood | 0% | 2.30 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0010765 | Biological process | positive regulation of sodium ion transport |
| GO_0006508 | Biological process | proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | PRSS8 |
| Protein name | Prostasin (EC 3.4.21.-) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain] Serine protease 8 |
| Synonyms | |
| Description | FUNCTION: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). . |
| Accessions | H3BUJ8 ENST00000567797.1 H3BVC8 ENST00000317508.11 [Q16651-1] ENST00000567531.5 Q16651 ENST00000568261.5 [Q16651-2] |