PRDM15 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	21% ± 4%	Explore
glutamatergic neuron	3 studies	28% ± 3%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	930.65	1445 / 1445	100%	3.78	183 / 183
uterus	100%	1066.07	170 / 170	100%	5.69	457 / 459
breast	100%	1047.83	459 / 459	100%	3.80	1113 / 1118
bladder	100%	902.43	21 / 21	99%	3.19	501 / 504
prostate	100%	1179.06	245 / 245	99%	2.70	497 / 502
skin	100%	1118.48	1809 / 1809	99%	4.46	467 / 472
intestine	100%	1144.57	966 / 966	98%	2.81	517 / 527
stomach	100%	742.62	359 / 359	98%	2.77	280 / 286
thymus	100%	1149.91	653 / 653	97%	2.71	589 / 605
lung	100%	958.78	578 / 578	97%	3.29	1124 / 1155
ovary	100%	1023.21	180 / 180	97%	4.45	417 / 430
pancreas	100%	531.71	328 / 328	97%	2.42	172 / 178
brain	97%	562.42	2552 / 2642	99%	3.09	696 / 705
kidney	100%	640.93	89 / 89	84%	1.76	761 / 901
adrenal gland	100%	798.17	258 / 258	73%	1.23	167 / 230
liver	100%	517.72	226 / 226	68%	1.77	277 / 406
adipose	100%	910.23	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	20.52	29 / 29
spleen	100%	1811.97	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	6.62	45 / 45
ureter	0%	0	0 / 0	100%	4.27	1 / 1
blood vessel	100%	806.51	1334 / 1335	0%	0	0 / 0
muscle	100%	988.60	802 / 803	0%	0	0 / 0
heart	98%	501.54	846 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	2.26	72 / 80
peripheral blood	83%	845.79	773 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0043409	Biological process	negative regulation of MAPK cascade
GO_0032259	Biological process	methylation
GO_2000035	Biological process	regulation of stem cell division
GO_0090263	Biological process	positive regulation of canonical Wnt signaling pathway
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_1990841	Molecular function	promoter-specific chromatin binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0046872	Molecular function	metal ion binding
GO_0008168	Molecular function	methyltransferase activity

Gene name	PRDM15
Protein name	PR/SET domain 15 PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298) PRDM15 protein PR/SET domain 15 (Zinc finger protein ZNF298d)
Synonyms	ZNF298 C21orf83
Description	FUNCTION: Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development (By similarity). Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming . .
Accessions	ENST00000398548.6 ENST00000422911.6 E7ER26 ENST00000441787.5 ENST00000491486.5 Q4W8S1 Q6NXF8 ENST00000447016.6 A0A6Q8PFK1 P57071 ENST00000269844.5 ENST00000449395.6

PRDM15 report