Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 8 studies | 22% ± 6% | |
plasmacytoid dendritic cell | 8 studies | 25% ± 9% | |
natural killer cell | 6 studies | 21% ± 6% | |
CD8-positive, alpha-beta memory T cell | 4 studies | 20% ± 3% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 20% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 23% ± 6% | |
hematopoietic precursor cell | 4 studies | 23% ± 7% | |
squamous epithelial cell | 3 studies | 32% ± 21% | |
B cell | 3 studies | 18% ± 1% | |
classical monocyte | 3 studies | 30% ± 11% | |
lymphocyte | 3 studies | 18% ± 4% | |
myeloid cell | 3 studies | 22% ± 5% | |
macrophage | 3 studies | 19% ± 5% | |
dendritic cell | 3 studies | 34% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5880.00 | 1445 / 1445 | 100% | 72.69 | 183 / 183 |
skin | 100% | 5681.50 | 1808 / 1809 | 100% | 84.92 | 471 / 472 |
intestine | 100% | 6391.92 | 966 / 966 | 99% | 59.38 | 524 / 527 |
ovary | 100% | 4346.91 | 180 / 180 | 99% | 48.60 | 427 / 430 |
stomach | 100% | 5105.66 | 359 / 359 | 99% | 64.08 | 284 / 286 |
lung | 100% | 6147.79 | 577 / 578 | 99% | 54.72 | 1147 / 1155 |
thymus | 100% | 6391.13 | 653 / 653 | 99% | 53.67 | 599 / 605 |
bladder | 100% | 5650.71 | 21 / 21 | 99% | 57.58 | 499 / 504 |
brain | 100% | 6597.32 | 2634 / 2642 | 99% | 41.41 | 700 / 705 |
uterus | 100% | 5330.15 | 170 / 170 | 99% | 53.41 | 453 / 459 |
breast | 100% | 4499.55 | 459 / 459 | 99% | 49.83 | 1103 / 1118 |
prostate | 100% | 5372.91 | 245 / 245 | 98% | 32.93 | 492 / 502 |
kidney | 100% | 4682.07 | 89 / 89 | 98% | 35.91 | 881 / 901 |
adrenal gland | 100% | 7518.53 | 258 / 258 | 97% | 67.69 | 224 / 230 |
pancreas | 97% | 2158.69 | 317 / 328 | 98% | 54.49 | 175 / 178 |
liver | 100% | 3115.80 | 225 / 226 | 94% | 29.92 | 382 / 406 |
adipose | 100% | 4575.19 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 57.10 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 122.43 | 29 / 29 |
muscle | 100% | 4447.73 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 12750.61 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 58.26 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.82 | 1 / 1 |
blood vessel | 100% | 4664.95 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 11467.20 | 928 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 3541.06 | 844 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043666 | Biological process | regulation of phosphoprotein phosphatase activity |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0019888 | Molecular function | protein phosphatase regulator activity |
GO_0005515 | Molecular function | protein binding |
GO_0019903 | Molecular function | protein phosphatase binding |
GO_0031267 | Molecular function | small GTPase binding |
Gene name | PPP6R1 |
Protein name | Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1) Protein phosphatase 6 regulatory subunit 1 |
Synonyms | SAPS1 KIAA1115 PP6R1 |
Description | FUNCTION: Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. . |
Accessions | ENST00000587283.5 K7EM28 ENST00000412770.7 ENST00000592242.1 Q9UPN7 |