Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 25% ± 8% | |
glutamatergic neuron | 6 studies | 31% ± 21% | |
microglial cell | 6 studies | 21% ± 7% | |
oligodendrocyte | 6 studies | 23% ± 7% | |
epithelial cell | 5 studies | 37% ± 16% | |
adipocyte | 5 studies | 21% ± 1% | |
interneuron | 5 studies | 30% ± 19% | |
cardiac muscle cell | 4 studies | 18% ± 1% | |
lymphocyte | 4 studies | 22% ± 7% | |
GABAergic neuron | 4 studies | 28% ± 14% | |
astrocyte | 4 studies | 25% ± 8% | |
endothelial cell of lymphatic vessel | 4 studies | 23% ± 6% | |
macrophage | 4 studies | 25% ± 9% | |
non-classical monocyte | 3 studies | 23% ± 6% | |
B cell | 3 studies | 18% ± 1% | |
neuron | 3 studies | 22% ± 2% | |
myeloid cell | 3 studies | 18% ± 2% | |
ciliated cell | 3 studies | 23% ± 2% | |
oligodendrocyte precursor cell | 3 studies | 28% ± 9% | |
monocyte | 3 studies | 17% ± 2% | |
fibroblast | 3 studies | 24% ± 7% | |
pericyte | 3 studies | 24% ± 10% | |
smooth muscle cell | 3 studies | 17% ± 1% | |
goblet cell | 3 studies | 34% ± 23% | |
transit amplifying cell | 3 studies | 35% ± 26% | |
granule cell | 3 studies | 19% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3549.78 | 258 / 258 | 100% | 17.22 | 230 / 230 |
bladder | 100% | 2455.24 | 21 / 21 | 100% | 15.73 | 504 / 504 |
breast | 100% | 2325.53 | 459 / 459 | 100% | 17.37 | 1118 / 1118 |
esophagus | 100% | 2365.60 | 1445 / 1445 | 100% | 13.02 | 183 / 183 |
kidney | 100% | 2177.03 | 89 / 89 | 100% | 13.66 | 901 / 901 |
lung | 100% | 2454.11 | 578 / 578 | 100% | 13.99 | 1155 / 1155 |
ovary | 100% | 4160.23 | 180 / 180 | 100% | 15.82 | 430 / 430 |
pancreas | 100% | 5206.43 | 328 / 328 | 100% | 13.30 | 178 / 178 |
prostate | 100% | 2671.74 | 245 / 245 | 100% | 23.75 | 502 / 502 |
stomach | 100% | 1738.71 | 359 / 359 | 100% | 11.79 | 286 / 286 |
thymus | 100% | 2367.81 | 653 / 653 | 100% | 16.91 | 605 / 605 |
uterus | 100% | 2312.39 | 170 / 170 | 100% | 16.43 | 459 / 459 |
brain | 100% | 2513.19 | 2639 / 2642 | 100% | 15.29 | 705 / 705 |
intestine | 100% | 2580.00 | 966 / 966 | 100% | 12.46 | 526 / 527 |
liver | 100% | 1349.46 | 226 / 226 | 100% | 8.39 | 405 / 406 |
skin | 100% | 2136.80 | 1808 / 1809 | 99% | 10.42 | 468 / 472 |
adipose | 100% | 2253.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 13.03 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.15 | 29 / 29 |
muscle | 100% | 2253.60 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2428.46 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.60 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.95 | 1 / 1 |
blood vessel | 100% | 2182.42 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 2005.55 | 853 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 1639.98 | 913 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051301 | Biological process | cell division |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0010458 | Biological process | exit from mitosis |
GO_0000159 | Cellular component | protein phosphatase type 2A complex |
GO_0005829 | Cellular component | cytosol |
GO_0019888 | Molecular function | protein phosphatase regulator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PPP2R2D |
Protein name | Protein phosphatase 2 regulatory subunit Bdelta Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
Synonyms | hCG_23640 KIAA1541 |
Description | FUNCTION: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). . |
Accessions | ENST00000616467.4 Q6IN90 ENST00000470416.5 A0A3B3IRK1 A0A0A6YYD6 Q66LE6 ENST00000482010.6 A0A096LPI9 ENST00000649083.1 Q6PEG1 ENST00000455566.6 H0YB06 |