POU3F1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of POU3F1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of POU3F1 at tissue level.

III. Associated gene sets

GO_0010628Biological processpositive regulation of gene expression
GO_0030216Biological processkeratinocyte differentiation
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030900Biological processforebrain development
GO_0022011Biological processmyelination in peripheral nervous system
GO_0008366Biological processaxon ensheathment
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding

IV. Literature review

[source]
Gene namePOU3F1
Protein namePOU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP)
SynonymsOTF6
OCT6
DescriptionFUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). Acts as a transcriptional repressor of myelin-specific genes (By similarity). .

AccessionsQ03052
ENST00000373012.5