I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| brush cell | 4 studies | 41% ± 22% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brush cell | 4 studies | 41% ± 22% |
Insufficient scRNA-seq data for expression of POU2AF2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 76% | 112.16 | 274 / 359 | 74% | 5.47 | 213 / 286 |
| intestine | 48% | 39.12 | 460 / 966 | 76% | 6.56 | 400 / 527 |
| pancreas | 33% | 9.51 | 107 / 328 | 89% | 7.99 | 158 / 178 |
| breast | 97% | 145.14 | 443 / 459 | 21% | 0.55 | 232 / 1118 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.06 | 1 / 1 |
| bladder | 29% | 6.90 | 6 / 21 | 66% | 9.14 | 331 / 504 |
| muscle | 83% | 37.50 | 664 / 803 | 0% | 0 | 0 / 0 |
| prostate | 58% | 17.71 | 142 / 245 | 18% | 0.44 | 91 / 502 |
| uterus | 16% | 9.51 | 28 / 170 | 52% | 8.37 | 237 / 459 |
| esophagus | 7% | 1.72 | 104 / 1445 | 53% | 4.75 | 97 / 183 |
| ovary | 48% | 20.72 | 86 / 180 | 10% | 0.31 | 42 / 430 |
| lung | 16% | 4.11 | 95 / 578 | 32% | 4.76 | 372 / 1155 |
| adipose | 47% | 27.36 | 564 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 42% | 6.47 | 19 / 45 |
| kidney | 17% | 3.49 | 15 / 89 | 8% | 1.65 | 70 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 61.01 | 5 / 29 |
| liver | 1% | 0.12 | 2 / 226 | 11% | 1.16 | 43 / 406 |
| spleen | 10% | 1.76 | 25 / 241 | 0% | 0 | 0 / 0 |
| thymus | 1% | 0.92 | 7 / 653 | 6% | 1.24 | 37 / 605 |
| skin | 3% | 0.62 | 46 / 1809 | 0% | 0.00 | 1 / 472 |
| adrenal gland | 1% | 0.20 | 2 / 258 | 2% | 1.14 | 4 / 230 |
| peripheral blood | 1% | 0.24 | 10 / 929 | 0% | 0 | 0 / 0 |
| heart | 1% | 0.15 | 8 / 861 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.09 | 13 / 2642 | 0% | 0.01 | 3 / 705 |
| blood vessel | 1% | 0.13 | 8 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0070974 | Molecular function | POU domain binding |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | POU2AF2 |
| Protein name | POU domain class 2-associating factor 2 (Oct coactivator from tuft cells 1) (Protein OCA-T1) (POU class 2 homeobox-associating factor 2) Chromosome 11 open reading frame 53 (POU class 2 homeobox associating factor 2) POU class 2 homeobox associating factor 2 |
| Synonyms | hCG_1642450 C11orf53 |
| Description | FUNCTION: Transcriptional coactivator of POU2F3 . This complex drives the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues . . |
| Accessions | ENST00000280325.7 Q8IXP5 ENST00000635886.1 A0A8V8SAS4 A0A1B0GU63 ENST00000637637.1 |
