I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 22% ± 5% | |
| glutamatergic neuron | 4 studies | 28% ± 5% | |
| astrocyte | 4 studies | 22% ± 6% | |
| interneuron | 3 studies | 25% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 22% ± 5% | |
| glutamatergic neuron | 4 studies | 28% ± 5% | |
| astrocyte | 4 studies | 22% ± 6% | |
| interneuron | 3 studies | 25% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 120.15 | 459 / 459 | 98% | 8.42 | 1100 / 1118 |
| ovary | 100% | 111.16 | 180 / 180 | 98% | 7.53 | 423 / 430 |
| uterus | 99% | 127.16 | 168 / 170 | 99% | 16.13 | 455 / 459 |
| stomach | 97% | 100.03 | 349 / 359 | 99% | 9.41 | 283 / 286 |
| intestine | 98% | 129.60 | 947 / 966 | 98% | 9.36 | 514 / 527 |
| esophagus | 93% | 144.27 | 1341 / 1445 | 100% | 12.40 | 183 / 183 |
| lung | 96% | 100.81 | 554 / 578 | 95% | 8.97 | 1102 / 1155 |
| bladder | 95% | 86.62 | 20 / 21 | 95% | 9.05 | 481 / 504 |
| skin | 100% | 282.73 | 1804 / 1809 | 90% | 5.84 | 427 / 472 |
| pancreas | 92% | 55.31 | 302 / 328 | 88% | 3.94 | 157 / 178 |
| prostate | 100% | 104.48 | 245 / 245 | 78% | 2.64 | 393 / 502 |
| thymus | 99% | 81.60 | 649 / 653 | 76% | 3.32 | 460 / 605 |
| liver | 100% | 115.62 | 225 / 226 | 74% | 4.39 | 299 / 406 |
| kidney | 91% | 59.76 | 81 / 89 | 47% | 1.61 | 422 / 901 |
| adrenal gland | 98% | 73.83 | 253 / 258 | 32% | 1.34 | 73 / 230 |
| brain | 72% | 32.46 | 1896 / 2642 | 57% | 3.18 | 399 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 12.06 | 29 / 29 |
| spleen | 100% | 157.26 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.45 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.61 | 1 / 1 |
| adipose | 99% | 88.84 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 91% | 54.93 | 1212 / 1335 | 0% | 0 | 0 / 0 |
| heart | 79% | 36.91 | 681 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 61% | 216.95 | 563 / 929 | 0% | 0 | 0 / 0 |
| muscle | 55% | 22.10 | 445 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 21% | 0.57 | 17 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006281 | Biological process | DNA repair |
| GO_0006260 | Biological process | DNA replication |
| GO_0042276 | Biological process | error-prone translesion synthesis |
| GO_0006261 | Biological process | DNA-templated DNA replication |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0008622 | Cellular component | epsilon DNA polymerase complex |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0003887 | Molecular function | DNA-directed DNA polymerase activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | POLE2 |
| Protein name | DNA polymerase epsilon 2, accessory subunit DNA polymerase II subunit 2 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) |
| Synonyms | DPE2 |
| Description | FUNCTION: Accessory component of the DNA polymerase epsilon complex . Participates in DNA repair and in chromosomal DNA replication (By similarity). . |
| Accessions | A0A8V8TQQ0 U3KQ22 ENST00000700175.1 P56282 A0A8V8TPE4 ENST00000554396.6 [P56282-3] ENST00000700176.1 A0A8V8TR10 ENST00000556937.5 ENST00000539565.6 [P56282-2] ENST00000553805.2 A0A8V8TPU0 ENST00000216367.10 [P56282-1] ENST00000700174.1 |
