POLDIP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045727Biological processpositive regulation of translation
GO_0016973Biological processpoly(A)+ mRNA export from nucleus
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0044877Molecular functionprotein-containing complex binding
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene namePOLDIP3
Protein namePolymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR)
DNA polymerase delta interacting protein 3 (Polymerase delta interacting protein 46)
POLDIP3 protein
DNA polymerase delta interacting protein 3
SynonymsKIAA1649
PDIP46
DescriptionFUNCTION: Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex. .

AccessionsF6VRR5
Q96DI9
Q6R954
Q8WUT1
Q9BY77
ENST00000252115.10 [Q9BY77-1]
F8WCX5
ENST00000348657.6 [Q9BY77-2]
ENST00000339677.10
ENST00000451060.6
ENST00000445215.5