POLDIP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045931Biological processpositive regulation of mitotic cell cycle
GO_0090307Biological processmitotic spindle assembly
GO_1903490Biological processpositive regulation of mitotic cytokinesis
GO_1990874Biological processvascular associated smooth muscle cell proliferation
GO_0007005Biological processmitochondrion organization
GO_0016242Biological processnegative regulation of macroautophagy
GO_0051894Biological processpositive regulation of focal adhesion assembly
GO_0070987Biological processerror-free translesion synthesis
GO_0005911Cellular componentcell-cell junction
GO_0072686Cellular componentmitotic spindle
GO_0030496Cellular componentmidbody
GO_0005759Cellular componentmitochondrial matrix
GO_0042645Cellular componentmitochondrial nucleoid
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePOLDIP2
Protein nameDNA polymerase delta interacting protein 2 (cDNA FLJ52257, highly similar to Polymerase delta-interacting protein 2)
Alternative protein POLDIP2
Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)
SynonymsPDIP38
HSPC017
POLD4
DescriptionFUNCTION: Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites . May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) . .

AccessionsB4DEM9
ENST00000618887.2
ENST00000540200.6
L8EAT8
Q9Y2S7