Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 28% ± 11% | |
| fibroblast | 4 studies | 19% ± 3% | |
| conventional dendritic cell | 3 studies | 20% ± 6% | |
| endothelial cell | 3 studies | 18% ± 0% | |
| ciliated cell | 3 studies | 22% ± 5% | |
| basal cell | 3 studies | 22% ± 4% | |
| dendritic cell | 3 studies | 25% ± 3% |
Insufficient scRNA-seq data for expression of PNO1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 770.27 | 180 / 180 | 100% | 35.71 | 430 / 430 |
| breast | 100% | 1293.25 | 459 / 459 | 100% | 37.89 | 1117 / 1118 |
| esophagus | 100% | 1001.50 | 1443 / 1445 | 100% | 35.91 | 183 / 183 |
| bladder | 100% | 1417.19 | 21 / 21 | 100% | 34.22 | 503 / 504 |
| uterus | 100% | 942.15 | 170 / 170 | 100% | 33.32 | 457 / 459 |
| intestine | 100% | 956.28 | 964 / 966 | 100% | 35.63 | 525 / 527 |
| lung | 99% | 1032.85 | 574 / 578 | 100% | 40.98 | 1155 / 1155 |
| stomach | 100% | 812.76 | 358 / 359 | 99% | 32.75 | 284 / 286 |
| thymus | 100% | 1004.67 | 652 / 653 | 99% | 22.54 | 600 / 605 |
| prostate | 100% | 1105.15 | 245 / 245 | 99% | 25.43 | 497 / 502 |
| brain | 99% | 709.54 | 2618 / 2642 | 100% | 25.86 | 704 / 705 |
| skin | 100% | 1283.56 | 1809 / 1809 | 99% | 34.81 | 465 / 472 |
| pancreas | 99% | 581.42 | 324 / 328 | 99% | 23.04 | 177 / 178 |
| kidney | 100% | 867.09 | 89 / 89 | 98% | 21.38 | 882 / 901 |
| liver | 98% | 619.12 | 221 / 226 | 99% | 17.26 | 402 / 406 |
| adrenal gland | 100% | 1353.85 | 258 / 258 | 95% | 18.82 | 218 / 230 |
| adipose | 100% | 1449.16 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.04 | 29 / 29 |
| spleen | 100% | 813.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 28.99 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.24 | 1 / 1 |
| muscle | 100% | 1312.95 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1121.47 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 95% | 719.18 | 818 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 19.70 | 76 / 80 |
| peripheral blood | 67% | 630.08 | 623 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042274 | Biological process | ribosomal small subunit biogenesis |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0032040 | Cellular component | small-subunit processome |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | PNO1 |
| Protein name | RNA-binding protein PNO1 (Partner of NOB1) Partner of NOB1 homolog |
| Synonyms | |
| Description | FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA . . |
| Accessions | ENST00000263657.7 ENST00000430742.1 F8WBJ6 Q9NRX1 |
