PLEKHG4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PLEKHG4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLEKHG4 at tissue level.

III. Associated gene sets

GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0007411Biological processaxon guidance
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0019898Cellular componentextrinsic component of membrane
GO_0005737Cellular componentcytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLEKHG4
Protein namePleckstrin homology and RhoGEF domain containing G4
Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1)
PLEKHG4 (Pleckstrin homology domain containing, family G (With RhoGef domain) member 4, isoform CRA_a)
Pleckstrin homology domain protein
SynonymsPRTPHN1
hCG_1811728
DescriptionFUNCTION: Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.

AccessionsENST00000379344.8 [Q58EX7-1]
A0A024R6X4
ENST00000360461.9 [Q58EX7-1]
ENST00000567136.1
ENST00000450733.5 [Q58EX7-2]
ENST00000568621.1
H3BQ60
ENST00000569875.5
ENST00000562744.1
ENST00000562144.5
J3QSC9
ENST00000567938.1
ENST00000563969.5 [Q58EX7-3]
H3BPQ5
C5IFI8
ENST00000565899.1
H3BQP9
H3BPA8
ENST00000393966.1 [Q58EX7-3]
H3BSU4
H3BME5
Q58EX7
ENST00000427155.6 [Q58EX7-1]
ENST00000565773.1
H3BQE6