Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 33% ± 19% | |
| ciliated cell | 10 studies | 38% ± 19% | |
| GABAergic neuron | 6 studies | 39% ± 19% | |
| glutamatergic neuron | 5 studies | 30% ± 10% | |
| interneuron | 5 studies | 35% ± 13% | |
| type II pneumocyte | 5 studies | 49% ± 9% | |
| endothelial cell | 4 studies | 41% ± 23% | |
| amacrine cell | 4 studies | 40% ± 13% | |
| Mueller cell | 4 studies | 48% ± 8% | |
| retina horizontal cell | 4 studies | 35% ± 14% | |
| GABAergic amacrine cell | 3 studies | 53% ± 8% | |
| retinal cone cell | 3 studies | 22% ± 9% | |
| retinal pigment epithelial cell | 3 studies | 29% ± 7% | |
| ependymal cell | 3 studies | 57% ± 5% | |
| type I pneumocyte | 3 studies | 17% ± 1% | |
| fibroblast | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 93% | 243.80 | 305 / 328 | 84% | 5.15 | 150 / 178 |
| kidney | 93% | 267.71 | 83 / 89 | 83% | 5.99 | 748 / 901 |
| lung | 88% | 532.86 | 506 / 578 | 79% | 8.59 | 910 / 1155 |
| stomach | 75% | 330.11 | 271 / 359 | 88% | 6.31 | 253 / 286 |
| brain | 96% | 815.74 | 2533 / 2642 | 67% | 4.50 | 474 / 705 |
| intestine | 69% | 270.43 | 665 / 966 | 92% | 6.59 | 487 / 527 |
| thymus | 99% | 922.77 | 647 / 653 | 50% | 4.22 | 301 / 605 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.24 | 1 / 1 |
| bladder | 38% | 102.48 | 8 / 21 | 55% | 3.83 | 278 / 504 |
| breast | 37% | 119.13 | 169 / 459 | 55% | 5.96 | 613 / 1118 |
| prostate | 47% | 92.32 | 116 / 245 | 18% | 0.75 | 90 / 502 |
| esophagus | 6% | 8.38 | 90 / 1445 | 58% | 4.65 | 106 / 183 |
| heart | 55% | 222.09 | 470 / 861 | 0% | 0 | 0 / 0 |
| ovary | 7% | 8.63 | 12 / 180 | 39% | 2.11 | 166 / 430 |
| uterus | 12% | 68.48 | 21 / 170 | 33% | 2.98 | 151 / 459 |
| skin | 10% | 13.37 | 176 / 1809 | 15% | 0.86 | 71 / 472 |
| muscle | 13% | 26.58 | 103 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.32 | 4 / 45 |
| liver | 0% | 0.49 | 1 / 226 | 6% | 0.18 | 24 / 406 |
| blood vessel | 4% | 5.77 | 47 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.18 | 2 / 80 |
| adrenal gland | 0% | 0.52 | 1 / 258 | 2% | 0.13 | 4 / 230 |
| peripheral blood | 2% | 3.26 | 17 / 929 | 0% | 0 | 0 / 0 |
| adipose | 1% | 0.79 | 8 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0046488 | Biological process | phosphatidylinositol metabolic process |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0048015 | Biological process | phosphatidylinositol-mediated signaling |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0050429 | Molecular function | calcium-dependent phospholipase C activity |
| GO_0004435 | Molecular function | phosphatidylinositol phospholipase C activity |
| Gene name | PLCH1 |
| Protein name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3) Phosphoinositide phospholipase C (EC 3.1.4.11) |
| Synonyms | KIAA1069 PLCL3 |
| Description | FUNCTION: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. . |
| Accessions | ENST00000460012.7 ENST00000447496.6 [Q4KWH8-3] ENST00000494598.5 [Q4KWH8-4] ENST00000340059.11 [Q4KWH8-1] Q4KWH8 ENST00000334686.6 [Q4KWH8-2] A0A2U3TZV8 |