Insufficient scRNA-seq data for expression of PLCD1 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 1738.71 | 653 / 653 | 100% | 30.23 | 603 / 605 |
| brain | 98% | 1480.73 | 2596 / 2642 | 100% | 45.46 | 705 / 705 |
| prostate | 100% | 1896.98 | 244 / 245 | 99% | 14.61 | 495 / 502 |
| breast | 100% | 1985.95 | 459 / 459 | 98% | 16.31 | 1091 / 1118 |
| ovary | 100% | 2313.07 | 180 / 180 | 97% | 14.94 | 418 / 430 |
| kidney | 100% | 1665.67 | 89 / 89 | 97% | 13.83 | 872 / 901 |
| bladder | 100% | 2770.29 | 21 / 21 | 96% | 34.74 | 484 / 504 |
| intestine | 100% | 2002.35 | 964 / 966 | 96% | 13.67 | 507 / 527 |
| uterus | 100% | 2157.35 | 170 / 170 | 96% | 21.72 | 440 / 459 |
| esophagus | 100% | 2520.91 | 1442 / 1445 | 95% | 15.30 | 173 / 183 |
| lung | 100% | 2202.69 | 577 / 578 | 94% | 16.03 | 1084 / 1155 |
| skin | 98% | 2512.40 | 1773 / 1809 | 95% | 14.05 | 450 / 472 |
| stomach | 99% | 1191.06 | 354 / 359 | 92% | 11.28 | 262 / 286 |
| pancreas | 84% | 600.61 | 274 / 328 | 99% | 15.75 | 176 / 178 |
| adrenal gland | 97% | 2084.41 | 251 / 258 | 84% | 7.92 | 194 / 230 |
| liver | 75% | 494.19 | 170 / 226 | 86% | 7.52 | 348 / 406 |
| adipose | 100% | 2152.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 18.82 | 80 / 80 |
| spleen | 100% | 1497.06 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 17.78 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.53 | 1 / 1 |
| blood vessel | 100% | 3856.06 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.01 | 28 / 29 |
| heart | 88% | 776.57 | 757 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 68% | 597.38 | 635 / 929 | 0% | 0 | 0 / 0 |
| muscle | 18% | 100.70 | 143 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006644 | Biological process | phospholipid metabolic process |
| GO_0048015 | Biological process | phosphatidylinositol-mediated signaling |
| GO_0046488 | Biological process | phosphatidylinositol metabolic process |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0032794 | Molecular function | GTPase activating protein binding |
| GO_0004435 | Molecular function | phosphatidylinositol phospholipase C activity |
| Gene name | PLCD1 |
| Protein name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1) |
| Synonyms | |
| Description | FUNCTION: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes . Essential for trophoblast and placental development (By similarity). Binds phosphatidylinositol 4,5-bisphosphate . . |
| Accessions | P51178 ENST00000463876.5 [P51178-2] ENST00000334661.5 [P51178-1] |
