Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 13 studies | 39% ± 22% | |
astrocyte | 11 studies | 29% ± 10% | |
oligodendrocyte precursor cell | 11 studies | 24% ± 6% | |
GABAergic neuron | 8 studies | 43% ± 18% | |
neuron | 7 studies | 34% ± 14% | |
amacrine cell | 7 studies | 35% ± 14% | |
interneuron | 6 studies | 43% ± 10% | |
retina horizontal cell | 6 studies | 32% ± 10% | |
cardiac muscle cell | 5 studies | 31% ± 6% | |
granule cell | 4 studies | 31% ± 6% | |
retinal ganglion cell | 4 studies | 26% ± 4% | |
endothelial cell | 3 studies | 39% ± 20% | |
GABAergic interneuron | 3 studies | 33% ± 17% | |
retinal bipolar neuron | 3 studies | 18% ± 3% | |
GABAergic amacrine cell | 3 studies | 39% ± 4% | |
Mueller cell | 3 studies | 33% ± 13% | |
ON-bipolar cell | 3 studies | 29% ± 5% | |
glycinergic amacrine cell | 3 studies | 35% ± 1% | |
neural progenitor cell | 3 studies | 20% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 6046.15 | 2632 / 2642 | 99% | 72.06 | 701 / 705 |
thymus | 97% | 2251.45 | 633 / 653 | 96% | 35.84 | 579 / 605 |
prostate | 45% | 509.87 | 111 / 245 | 98% | 23.38 | 494 / 502 |
bladder | 62% | 612.52 | 13 / 21 | 64% | 19.87 | 322 / 504 |
muscle | 100% | 19762.26 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.83 | 1 / 1 |
heart | 93% | 4621.65 | 803 / 861 | 0% | 0 | 0 / 0 |
lung | 25% | 255.62 | 143 / 578 | 52% | 8.11 | 598 / 1155 |
adrenal gland | 5% | 59.13 | 14 / 258 | 70% | 64.94 | 160 / 230 |
tonsil | 0% | 0 | 0 / 0 | 73% | 13.78 | 33 / 45 |
pancreas | 0% | 0 | 0 / 328 | 69% | 8.83 | 122 / 178 |
uterus | 3% | 23.69 | 5 / 170 | 57% | 11.84 | 261 / 459 |
skin | 30% | 338.51 | 549 / 1809 | 25% | 4.19 | 117 / 472 |
ovary | 21% | 188.86 | 37 / 180 | 32% | 3.66 | 139 / 430 |
lymph node | 0% | 0 | 0 / 0 | 52% | 5.14 | 15 / 29 |
kidney | 3% | 33.64 | 3 / 89 | 39% | 9.90 | 351 / 901 |
breast | 7% | 75.02 | 34 / 459 | 28% | 6.48 | 316 / 1118 |
intestine | 13% | 119.47 | 126 / 966 | 20% | 2.27 | 107 / 527 |
esophagus | 10% | 89.29 | 143 / 1445 | 23% | 2.70 | 42 / 183 |
stomach | 0% | 2.14 | 1 / 359 | 23% | 2.48 | 67 / 286 |
peripheral blood | 15% | 161.73 | 142 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 11% | 1.37 | 9 / 80 |
liver | 0% | 0 | 0 / 226 | 5% | 0.86 | 20 / 406 |
blood vessel | 1% | 27.78 | 16 / 1335 | 0% | 0 | 0 / 0 |
adipose | 0% | 2.52 | 4 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0141162 | Biological process | negative regulation of cAMP/PKA signal transduction |
GO_0042308 | Biological process | negative regulation of protein import into nucleus |
GO_0010389 | Biological process | regulation of G2/M transition of mitotic cell cycle |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_2000480 | Biological process | negative regulation of cAMP-dependent protein kinase activity |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004862 | Molecular function | cAMP-dependent protein kinase inhibitor activity |
GO_0034236 | Molecular function | protein kinase A catalytic subunit binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PKIA |
Protein name | cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform) |
Synonyms | PRKACN1 |
Description | FUNCTION: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. |
Accessions | P61925 ENST00000518467.1 ENST00000352966.9 ENST00000396418.7 |