PKIA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0141162Biological processnegative regulation of cAMP/PKA signal transduction
GO_0042308Biological processnegative regulation of protein import into nucleus
GO_0010389Biological processregulation of G2/M transition of mitotic cell cycle
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_2000480Biological processnegative regulation of cAMP-dependent protein kinase activity
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004862Molecular functioncAMP-dependent protein kinase inhibitor activity
GO_0034236Molecular functionprotein kinase A catalytic subunit binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePKIA
Protein namecAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform)
SynonymsPRKACN1
DescriptionFUNCTION: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

AccessionsP61925
ENST00000518467.1
ENST00000352966.9
ENST00000396418.7