Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 18% ± 3% | |
| oligodendrocyte | 6 studies | 24% ± 6% | |
| adipocyte | 5 studies | 21% ± 2% | |
| astrocyte | 5 studies | 37% ± 11% | |
| fibroblast | 4 studies | 24% ± 7% | |
| cardiac muscle cell | 4 studies | 23% ± 3% | |
| epithelial cell | 3 studies | 44% ± 13% | |
| basal cell | 3 studies | 37% ± 14% | |
| ciliated cell | 3 studies | 34% ± 6% | |
| retinal pigment epithelial cell | 3 studies | 26% ± 6% | |
| endothelial cell of artery | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 37% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 98% | 601.07 | 1773 / 1809 | 94% | 147.33 | 444 / 472 |
| liver | 99% | 733.98 | 224 / 226 | 92% | 33.52 | 375 / 406 |
| prostate | 100% | 694.13 | 245 / 245 | 91% | 15.00 | 457 / 502 |
| uterus | 100% | 729.91 | 170 / 170 | 90% | 40.55 | 414 / 459 |
| bladder | 100% | 1862.76 | 21 / 21 | 88% | 42.41 | 446 / 504 |
| adrenal gland | 100% | 1197.20 | 257 / 258 | 87% | 19.45 | 200 / 230 |
| lung | 100% | 1028.15 | 577 / 578 | 84% | 41.03 | 966 / 1155 |
| esophagus | 100% | 1142.58 | 1444 / 1445 | 83% | 27.07 | 151 / 183 |
| intestine | 99% | 590.36 | 959 / 966 | 76% | 13.64 | 401 / 527 |
| brain | 99% | 915.59 | 2627 / 2642 | 76% | 15.53 | 533 / 705 |
| breast | 100% | 983.80 | 459 / 459 | 73% | 17.37 | 819 / 1118 |
| kidney | 100% | 645.87 | 89 / 89 | 71% | 11.44 | 638 / 901 |
| stomach | 96% | 578.82 | 343 / 359 | 71% | 12.97 | 204 / 286 |
| ovary | 99% | 782.43 | 179 / 180 | 59% | 10.63 | 255 / 430 |
| thymus | 100% | 1096.47 | 652 / 653 | 59% | 11.90 | 355 / 605 |
| adipose | 100% | 1170.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 231.05 | 80 / 80 |
| spleen | 100% | 1274.97 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 17.98 | 1 / 1 |
| blood vessel | 100% | 913.86 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 654.06 | 850 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 40.49 | 44 / 45 |
| muscle | 98% | 573.62 | 784 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 26% | 62.57 | 86 / 328 | 61% | 11.77 | 108 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 4.21 | 9 / 29 |
| peripheral blood | 20% | 221.07 | 188 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0030224 | Biological process | monocyte differentiation |
| GO_0007586 | Biological process | digestion |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0008127 | Molecular function | quercetin 2,3-dioxygenase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003712 | Molecular function | transcription coregulator activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | PIR |
| Protein name | Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase) |
| Synonyms | |
| Description | FUNCTION: Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). . |
| Accessions | O00625 ENST00000380420.10 ENST00000380421.3 |