PIGN | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	11 studies	30% ± 12%	Explore
astrocyte	10 studies	31% ± 17%	Explore
endothelial cell	9 studies	24% ± 9%	Explore
oligodendrocyte precursor cell	9 studies	26% ± 10%	Explore
glutamatergic neuron	8 studies	39% ± 24%	Explore
microglial cell	7 studies	24% ± 7%	Explore
epithelial cell	6 studies	32% ± 16%	Explore
adipocyte	6 studies	22% ± 5%	Explore
GABAergic neuron	6 studies	35% ± 19%	Explore
macrophage	5 studies	29% ± 6%	Explore
endothelial cell of lymphatic vessel	4 studies	19% ± 3%	Explore
fibroblast	4 studies	23% ± 5%	Explore
interneuron	4 studies	40% ± 21%	Explore
myeloid cell	3 studies	21% ± 4%	Explore
cardiac muscle cell	3 studies	22% ± 2%	Explore
retinal bipolar neuron	3 studies	21% ± 6%	Explore
pericyte	3 studies	19% ± 4%	Explore
type I pneumocyte	3 studies	22% ± 4%	Explore
type II pneumocyte	3 studies	19% ± 3%	Explore
basal cell	3 studies	29% ± 15%	Explore
goblet cell	3 studies	30% ± 19%	Explore
transit amplifying cell	3 studies	37% ± 22%	Explore
smooth muscle cell	3 studies	19% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	11 studies	33% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	1661.86	245 / 245	100%	9.77	500 / 502
breast	100%	1306.53	459 / 459	98%	8.87	1100 / 1118
brain	99%	737.82	2604 / 2642	97%	4.56	686 / 705
lung	99%	993.46	575 / 578	96%	5.84	1112 / 1155
esophagus	100%	1662.95	1445 / 1445	95%	5.74	173 / 183
bladder	100%	1418.90	21 / 21	94%	5.38	475 / 504
uterus	100%	1148.86	170 / 170	94%	5.63	430 / 459
stomach	100%	1624.18	359 / 359	93%	4.39	265 / 286
pancreas	100%	1064.49	327 / 328	93%	4.06	165 / 178
intestine	100%	1113.49	965 / 966	91%	4.58	481 / 527
thymus	100%	1386.46	653 / 653	91%	3.90	550 / 605
skin	100%	2267.90	1809 / 1809	90%	6.03	427 / 472
kidney	100%	792.91	89 / 89	81%	3.65	731 / 901
ovary	100%	1311.56	180 / 180	77%	2.96	329 / 430
adrenal gland	100%	1273.78	258 / 258	70%	2.34	161 / 230
liver	99%	716.03	223 / 226	70%	2.66	283 / 406
adipose	100%	1200.55	1204 / 1204	0%	0	0 / 0
spleen	100%	983.30	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.01	1 / 1
blood vessel	100%	934.75	1330 / 1335	0%	0	0 / 0
muscle	100%	836.22	799 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	7.35	44 / 45
heart	97%	910.89	832 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	4.15	24 / 29
peripheral blood	68%	717.60	636 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	63%	2.59	50 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	PIGN
Protein name	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)
Synonyms	MCD4
Description	FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. . FUNCTION: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. .
Accessions	A0A1W2PQZ1 ENST00000585458.2 ENST00000638369.1 ENST00000589720.6 ENST00000640252.2 K7EID9 K7EMD7 K7EL34 A0A1W2PQA9 A0A1W2PNQ8 ENST00000639681.1 A0A1W2PRH3 ENST00000586566.2 K7ESH9 A0A1W2PNH8 ENST00000590765.5 ENST00000640145.1 ENST00000638329.1 ENST00000640876.1 A0A1W2PPB6 ENST00000591238.6 ENST00000592803.2 ENST00000585344.6 ENST00000638183.1 A0A1W2PR74 A0A1W2PPR7 ENST00000639372.1 ENST00000639174.1 ENST00000639912.1 ENST00000640593.1 ENST00000400334.7 ENST00000638591.1 ENST00000588571.6 ENST00000638167.1 ENST00000639758.1 A0A1W2PQP4 A0A1W2PPK6 ENST00000638904.1 ENST00000639902.1 ENST00000640268.1 ENST00000640540.1 ENST00000589339.6 K7ERX5 ENST00000640170.1 A0A1W2PPA0 ENST00000638936.1 A0A1W2PQ49 A0A1W2PS19 K7ELE1 ENST00000638424.1 K7EJM6 ENST00000639342.1 K7ENK2 K7EPJ2 ENST00000585926.5 ENST00000357637.10 ENST00000638977.1 ENST00000640682.1 A0A1W2PQR8 A0A1W2PNR0 O95427 ENST00000639600.1 K7EQG0 ENST00000638435.1 ENST00000640050.1 ENST00000585923.6 A0A1W2PNW5 ENST00000590948.5

GO_0016254	Biological process	preassembly of GPI anchor in ER membrane
GO_0006506	Biological process	GPI anchor biosynthetic process
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0051377	Molecular function	mannose-ethanolamine phosphotransferase activity

PIGN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review