PIGA report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PIGA at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PIGA at tissue level.

III. Associated gene sets

GO_0016254Biological processpreassembly of GPI anchor in ER membrane
GO_1990830Biological processcellular response to leukemia inhibitory factor
GO_0006506Biological processGPI anchor biosynthetic process
GO_0000506Cellular componentglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0008194Molecular functionUDP-glycosyltransferase activity
GO_0017176Molecular functionphosphatidylinositol N-acetylglucosaminyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePIGA
Protein namePIGA mutant 02405
phosphatidylinositol N-acetylglucosaminyltransferase (EC 2.4.1.198) (GlcNAc-PI synthesis protein)
Phosphatidylinositol glycan anchor biosynthesis class A
PIGA mutant A425
PIGA mutant 28803
PIGA mutant 02816
Phosphatidylinositol glycan anchor biosynthesis class A (cDNA FLJ76386, highly similar to Homo sapiens phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) (PIGA), transcript variant 2, mRNA)
PIGA mutant A413
PIGA mutant 02410 (PIGA mutant 02811) (PIGA mutant 02812) (PIGA mutant 28805) (PIGA mutant 28806)
PIGA mutant A421
PIGA mutant 02408
PIGA mutant 28401
PIGA mutant 02409
PIGA mutant 28807 (PIGA mutant 37408) (PIGA mutant 37409) (PIGA mutant 37410) (PIGA mutant A426) (PIGA mutant A427)
PIGA mutant 02402
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A)
PIGA mutant A407
PIGA mutant 02808 (PIGA mutant 02809) (PIGA mutant 37406) (PIGA mutant A420)
PIGA mutant A412
PIGA mutant
Phosphatidylinositol glycan anchor biosynthesis class A (Phosphatidylinositol glycan, class A (Paroxysmal nocturnal hemoglobinuria), isoform CRA_b) (cDNA FLJ40728 fis, clone TKIDN2000240, highly similar to Phosphatidylinositol N-acetylglucosaminyltransferase subunit A)
PIGA mutant A801
PIGA mutant 37402 (PIGA mutant 37403) (PIGA mutant 37404)
PIGA mutant 02810
PIGA mutant 02815
PIGA mutant A430
PIGA mutant 02803
PIGA mutant 02813 (PIGA mutant 02814)
PIGA mutant 02807
SynonymshCG_1783055
DescriptionFUNCTION: Catalytic subunit of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. .

AccessionsENST00000333590.6 [P37287-1]
ENST00000637626.1
A0A2K4Z9X9
A0A2K4Z9Q2
A0A2K4Z9V8
A0A2K4Z9W3
A0A2K4Z9Z7
A0A2K4Z9T8
A0A2K4Z9Z0
ENST00000638131.1
A0A2K4Z9P3
A0A2K4Z9V9
A0A2K4Z9S0
A0A2K4Z9X5
A0A2K4Z9P8
A0A2K4Z9T0
A0A2K4Z9R1
A0A0U1RQW8
A0A2K4Z9X4
A0A2K4Z9W2
A0A2K4Z9W5
A0A2K4ZA03
A0A2K4Z9Y2
A0A2K4ZA10
A0A2K4Z9P5
A0A2K4Z9U3
A0A2K4Z9T5
A0A2K4Z9V3
A0A2K4ZA04
A0A2K4Z9P4
A0A2K4Z9P9
A0A2K4Z9W0
A0A1B0GVE5
A0A2K4Z9W1
A0A2K4Z9Z2
A0A2K4Z9Y7
A0A2K4Z9R6
ENST00000634582.1 [P37287-3]
A0A2K4Z9P6
A0A2K4Z9Z6
ENST00000634640.1
ENST00000635543.1
A0A2K4Z9Y4
A0A2K4Z9Q7
P37287
A0A2K4Z9W7
A0A2K4Z9Q9
A0A2K4Z9X8
A0A2K4Z9R8
B3KUV7
A0A2K4Z9X6
ENST00000482148.6 [P37287-2]
A8K382
A0A2K4Z9S8
A0A1B0GU19
A0A2K4Z9V6
ENST00000635598.1
A0A2K4Z9W8
A0A2K4Z9X7
A0A2K4Z9U0
A0A2K4Z9U9
A0A2K4Z9Y3
ENST00000637296.1
ENST00000542278.6 [P37287-1]
A0A2K4Z9Y8
A0A2K4ZA05
A0A2K4ZA07
A0A2K4Z9T4
A0A2K4Z9Y1
ENST00000634286.1
A0A2K4Z9T7
A0A2K4Z9S5
A0A2K4Z9Y9
A0A2K4Z9U6
A0A2K4ZA02
A0A2K4ZA29
A0A2K4Z9X1
A0A2K4Z9U2
A0A2K4ZA01
A0A0U1RQM9
A0A2K4Z9V4
A0A2K4Z9X3
A0A2K4ZA06
A0A2K4Z9V5
A0A0U1RRE8
A0A2K4Z9T1
A0A2K4Z9Z5
A0A2K4Z9Z9
ENST00000475746.1
A0A2K4Z9U4
A0A0U1RQF5