glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

I. Literature review

[source]
Nameglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
IDGO_0000506
collection_id

Cellular component

Exact synonym

GPI-GlcNAc transferase complex, GPI-GnT complex, GPI-N-acetylglucosaminyltransferase complex

Description

An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.

Comment

Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity.

External URL
Genes
PIGADPM2PIGHPIGQPIGCPIGPPIGY