PIEZO2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006812Biological processmonoatomic cation transport
GO_0050982Biological processdetection of mechanical stimulus
GO_0009612Biological processresponse to mechanical stimulus
GO_0050974Biological processdetection of mechanical stimulus involved in sensory perception
GO_0042391Biological processregulation of membrane potential
GO_0071260Biological processcellular response to mechanical stimulus
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_0005886Cellular componentplasma membrane
GO_0008381Molecular functionmechanosensitive monoatomic ion channel activity
GO_0005261Molecular functionmonoatomic cation channel activity

IV. Literature review

[source]
Gene namePIEZO2
Protein namePiezo-type mechanosensitive ion channel component 2 (Protein FAM38B)
Piezo type mechanosensitive ion channel component 2
PIEZO2 variant 16 (Piezo type mechanosensitive ion channel component 2)
Piezo-type mechanosensitive ion channel component 2
SynonymsC18orf58
FAM38B
C18orf30
DescriptionFUNCTION: Pore-forming subunit of a mechanosensitive non-specific cation channel required for rapidly adapting mechanically activated (MA) currents and has a key role in sensing touch and tactile pain. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. .

AccessionsENST00000503781.7 [Q9H5I5-1]
J3KRQ5
A0A2R8Y3N5
ENST00000579949.2
A0A8I5KT39
ENST00000581680.1
ENST00000302079.10 [Q9H5I5-2]
ENST00000580640.5 [Q9H5I5-4]
J3KRW1
V9GZ18
J3QLJ9
ENST00000582937.1
ENST00000643712.1
ENST00000674853.1
ENST00000579112.1
A0A2H4UKA7
E7EVM7
ENST00000383408
ENST00000693743.1
Q9H5I5
A0A2R8YG64
ENST00000582913.5