PHYH | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	6 studies	27% ± 7%	Explore
epithelial cell of proximal tubule	5 studies	34% ± 7%	Explore
endothelial cell	4 studies	18% ± 3%	Explore
enterocyte	3 studies	21% ± 1%	Explore
fibroblast	3 studies	23% ± 5%	Explore
macrophage	3 studies	25% ± 6%	Explore
mast cell	3 studies	19% ± 5%	Explore
hepatocyte	3 studies	47% ± 34%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PHYH at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	9232.96	226 / 226	100%	207.31	406 / 406
kidney	100%	6145.33	89 / 89	99%	64.84	896 / 901
adrenal gland	100%	4795.81	258 / 258	99%	51.65	228 / 230
thymus	100%	2805.23	652 / 653	99%	51.72	600 / 605
stomach	100%	1885.33	359 / 359	98%	35.94	281 / 286
pancreas	98%	1260.30	322 / 328	100%	30.64	178 / 178
breast	100%	2429.10	459 / 459	98%	39.20	1097 / 1118
prostate	99%	1261.46	242 / 245	99%	40.06	497 / 502
intestine	100%	2469.08	965 / 966	98%	34.64	515 / 527
bladder	100%	1980.29	21 / 21	96%	36.45	485 / 504
ovary	100%	1972.63	180 / 180	96%	24.33	411 / 430
brain	96%	1439.65	2548 / 2642	95%	25.07	667 / 705
lung	95%	1335.34	550 / 578	96%	26.28	1106 / 1155
skin	98%	1307.83	1780 / 1809	90%	21.12	426 / 472
uterus	99%	1541.04	169 / 170	82%	27.22	376 / 459
esophagus	80%	1519.94	1152 / 1445	84%	19.79	154 / 183
adipose	100%	2690.80	1204 / 1204	0%	0	0 / 0
muscle	100%	12660.69	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	14.88	1 / 1
blood vessel	100%	2017.75	1331 / 1335	0%	0	0 / 0
heart	97%	4424.88	836 / 861	0%	0	0 / 0
spleen	96%	883.63	231 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	88%	19.28	70 / 80
lymph node	0%	0	0 / 0	86%	18.11	25 / 29
tonsil	0%	0	0 / 0	51%	6.58	23 / 45
peripheral blood	21%	196.02	196 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006720	Biological process	isoprenoid metabolic process
GO_0006103	Biological process	2-oxoglutarate metabolic process
GO_0019606	Biological process	2-oxobutyrate catabolic process
GO_0097089	Biological process	methyl-branched fatty acid metabolic process
GO_0001561	Biological process	fatty acid alpha-oxidation
GO_0097731	Cellular component	9+0 non-motile cilium
GO_0005829	Cellular component	cytosol
GO_0005777	Cellular component	peroxisome
GO_0005782	Cellular component	peroxisomal matrix
GO_0048244	Molecular function	phytanoyl-CoA dioxygenase activity
GO_0031406	Molecular function	carboxylic acid binding
GO_0008198	Molecular function	ferrous iron binding
GO_0005515	Molecular function	protein binding
GO_0031418	Molecular function	L-ascorbic acid binding

Gene name	PHYH
Protein name	Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) phytanoyl-CoA dioxygenase (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase)
Synonyms	PAHX
Description	FUNCTION: Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono-branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms) . Does not hydroxylate long and very long straight chain acyl-CoAs or 2-methyl- and 4-methyl-branched acyl-CoAs . .
Accessions	C9IYS5 ENST00000396920.7 B1ALH6 O14832 ENST00000453759.6 C9JR86 ENST00000479604.1 Q6FGQ2 ENST00000396913.6 [O14832-2] ENST00000263038.9 [O14832-1]

PHYH report