Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 26% ± 4% | |
| retinal rod cell | 5 studies | 20% ± 4% | |
| microglial cell | 5 studies | 22% ± 6% | |
| astrocyte | 4 studies | 28% ± 9% | |
| glutamatergic neuron | 4 studies | 39% ± 9% | |
| oligodendrocyte precursor cell | 4 studies | 22% ± 5% | |
| macrophage | 4 studies | 20% ± 3% | |
| oligodendrocyte | 4 studies | 25% ± 5% | |
| B cell | 3 studies | 20% ± 2% | |
| non-classical monocyte | 3 studies | 27% ± 11% | |
| endothelial cell | 3 studies | 18% ± 2% | |
| retinal cone cell | 3 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 34% ± 3% | |
| basal cell | 3 studies | 22% ± 4% | |
| plasmacytoid dendritic cell | 3 studies | 21% ± 3% | |
| interneuron | 3 studies | 33% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1370.53 | 1445 / 1445 | 100% | 8.09 | 183 / 183 |
| prostate | 100% | 1298.54 | 245 / 245 | 100% | 10.72 | 502 / 502 |
| lung | 100% | 1277.49 | 577 / 578 | 100% | 7.84 | 1155 / 1155 |
| breast | 100% | 1390.80 | 459 / 459 | 100% | 13.64 | 1116 / 1118 |
| brain | 100% | 932.29 | 2637 / 2642 | 100% | 11.44 | 705 / 705 |
| uterus | 100% | 1467.76 | 170 / 170 | 100% | 7.54 | 457 / 459 |
| thymus | 100% | 1299.07 | 653 / 653 | 99% | 7.51 | 600 / 605 |
| adrenal gland | 100% | 1671.77 | 258 / 258 | 99% | 8.50 | 228 / 230 |
| kidney | 100% | 1038.09 | 89 / 89 | 99% | 9.17 | 889 / 901 |
| bladder | 100% | 1378.57 | 21 / 21 | 99% | 7.59 | 497 / 504 |
| pancreas | 100% | 740.46 | 327 / 328 | 98% | 7.99 | 175 / 178 |
| stomach | 100% | 1169.07 | 359 / 359 | 98% | 8.27 | 279 / 286 |
| liver | 100% | 875.81 | 226 / 226 | 98% | 5.33 | 396 / 406 |
| intestine | 100% | 1611.82 | 966 / 966 | 97% | 8.14 | 510 / 527 |
| ovary | 100% | 1212.43 | 180 / 180 | 96% | 4.20 | 412 / 430 |
| skin | 100% | 1229.22 | 1809 / 1809 | 94% | 7.37 | 442 / 472 |
| blood vessel | 100% | 1260.73 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.02 | 29 / 29 |
| spleen | 100% | 1755.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.62 | 1 / 1 |
| adipose | 100% | 1357.48 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 868.82 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 810.34 | 855 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 6.98 | 44 / 45 |
| peripheral blood | 83% | 836.15 | 772 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 68% | 3.48 | 54 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0018344 | Biological process | protein geranylgeranylation |
| GO_0005953 | Cellular component | CAAX-protein geranylgeranyltransferase complex |
| GO_0004661 | Molecular function | protein geranylgeranyltransferase activity |
| GO_0004662 | Molecular function | CAAX-protein geranylgeranyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | PGGT1B |
| Protein name | Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B. . |
| Accessions | P53609 ENST00000379615.3 [P53609-2] ENST00000419445.6 [P53609-1] |