PGGT1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0018344Biological processprotein geranylgeranylation
GO_0005953Cellular componentCAAX-protein geranylgeranyltransferase complex
GO_0004661Molecular functionprotein geranylgeranyltransferase activity
GO_0004662Molecular functionCAAX-protein geranylgeranyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene namePGGT1B
Protein nameGeranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta)
Synonyms
DescriptionFUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B. .

AccessionsP53609
ENST00000379615.3 [P53609-2]
ENST00000419445.6 [P53609-1]