PEG3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0010468Biological processregulation of gene expression
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005776Cellular componentautophagosome
GO_0005634Cellular componentnucleus
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene namePEG3
Protein namePEG3 protein
Paternally expressed 3
Alternative protein PEG3
Paternally-expressed gene 3 protein (Zinc finger and SCAN domain-containing protein 24)
SynonymsKIAA0287
ZSCAN24
DescriptionFUNCTION: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells. .

AccessionsM0QZD4
ENST00000649428.1 [Q9GZU2-4]
ENST00000649680.1 [Q9GZU2-4]
ENST00000649233.1 [Q9GZU2-4]
L8EAH8
ENST00000600833.2
B9EG68
ENST00000599534.5 [Q9GZU2-1]
ENST00000599577.5 [Q9GZU2-1]
ENST00000326441.15 [Q9GZU2-1]
Q9GZU2
ENST00000650632.1 [Q9GZU2-4]
M0QXG1
A0A3B3ITJ6
ENST00000650102.1 [Q9GZU2-4]
ENST00000593695.5 [Q9GZU2-2]
ENST00000648694.1 [Q9GZU2-4]
ENST00000649735.1
ENST00000647852.1
ENST00000598410.5 [Q9GZU2-4]
A0A3B3ISL2
ENST00000594389.1
A0A3B3IRU6
ENST00000649876.1 [Q9GZU2-4]
ENST00000647621.1