PDXK report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009443Biological processpyridoxal 5'-phosphate salvage
GO_0042817Biological processpyridoxal metabolic process
GO_0042818Biological processpyridoxamine metabolic process
GO_0005576Cellular componentextracellular region
GO_0035580Cellular componentspecific granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0034774Cellular componentsecretory granule lumen
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0042803Molecular functionprotein homodimerization activity
GO_0030170Molecular functionpyridoxal phosphate binding
GO_0008478Molecular functionpyridoxal kinase activity
GO_0000287Molecular functionmagnesium ion binding
GO_0031403Molecular functionlithium ion binding
GO_0030955Molecular functionpotassium ion binding
GO_0008270Molecular functionzinc ion binding
GO_0005524Molecular functionATP binding
GO_0031402Molecular functionsodium ion binding

IV. Literature review

[source]
Gene namePDXK
Protein namePyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase)
Pyridoxal kinase
HCG401289, isoform CRA_e (Pyridoxal kinase)
pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase)
SynonymsPKH
C21orf97
PNK
PRED79
C21orf124
hCG_401289
DescriptionFUNCTION: Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions. .

AccessionsA8MV33
ENST00000621478.1
A8MT14
ENST00000467908.1
ENST00000291565.9 [O00764-1]
ENST00000327574.4
ENST00000468090.5 [O00764-2]
O00764
A0A0B4J2C9
G1UI32
ENST00000398081.5
F2Z2Y4