Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 27 studies | 28% ± 10% | |
endothelial cell | 16 studies | 34% ± 15% | |
classical monocyte | 15 studies | 26% ± 13% | |
ciliated cell | 13 studies | 31% ± 12% | |
myeloid cell | 12 studies | 29% ± 11% | |
type I pneumocyte | 11 studies | 40% ± 10% | |
basal cell | 11 studies | 28% ± 14% | |
epithelial cell | 11 studies | 35% ± 15% | |
plasma cell | 10 studies | 28% ± 13% | |
adipocyte | 9 studies | 38% ± 6% | |
alveolar macrophage | 8 studies | 28% ± 9% | |
glutamatergic neuron | 8 studies | 39% ± 24% | |
astrocyte | 8 studies | 27% ± 9% | |
monocyte | 7 studies | 26% ± 5% | |
club cell | 7 studies | 24% ± 9% | |
respiratory goblet cell | 7 studies | 25% ± 14% | |
secretory cell | 7 studies | 30% ± 13% | |
non-classical monocyte | 7 studies | 31% ± 17% | |
microglial cell | 6 studies | 25% ± 8% | |
fibroblast | 6 studies | 25% ± 3% | |
type II pneumocyte | 6 studies | 28% ± 11% | |
GABAergic neuron | 6 studies | 40% ± 22% | |
goblet cell | 6 studies | 28% ± 17% | |
mononuclear phagocyte | 5 studies | 20% ± 3% | |
plasmablast | 4 studies | 39% ± 15% | |
squamous epithelial cell | 4 studies | 32% ± 23% | |
conventional dendritic cell | 4 studies | 21% ± 6% | |
neuron | 4 studies | 24% ± 9% | |
retinal ganglion cell | 4 studies | 48% ± 19% | |
mucus secreting cell | 4 studies | 22% ± 3% | |
kidney loop of Henle epithelial cell | 3 studies | 27% ± 11% | |
amacrine cell | 3 studies | 19% ± 4% | |
tissue-resident macrophage | 3 studies | 21% ± 0% | |
dendritic cell | 3 studies | 36% ± 11% | |
abnormal cell | 3 studies | 28% ± 5% | |
leukocyte | 3 studies | 24% ± 3% | |
transit amplifying cell | 3 studies | 30% ± 17% | |
interneuron | 3 studies | 45% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 5434.60 | 359 / 359 | 100% | 48.09 | 286 / 286 |
uterus | 100% | 5374.87 | 170 / 170 | 100% | 60.62 | 459 / 459 |
brain | 100% | 15754.22 | 2639 / 2642 | 100% | 58.76 | 705 / 705 |
pancreas | 100% | 5422.29 | 327 / 328 | 100% | 45.83 | 178 / 178 |
intestine | 100% | 5843.07 | 963 / 966 | 100% | 51.70 | 527 / 527 |
thymus | 100% | 8226.69 | 653 / 653 | 100% | 50.76 | 603 / 605 |
bladder | 100% | 4671.00 | 21 / 21 | 100% | 53.79 | 502 / 504 |
prostate | 100% | 7273.56 | 244 / 245 | 100% | 31.01 | 502 / 502 |
kidney | 100% | 9717.19 | 89 / 89 | 100% | 36.60 | 897 / 901 |
lung | 99% | 9832.46 | 575 / 578 | 100% | 42.86 | 1155 / 1155 |
breast | 100% | 8311.61 | 457 / 459 | 100% | 42.77 | 1116 / 1118 |
skin | 100% | 5591.16 | 1801 / 1809 | 100% | 31.20 | 471 / 472 |
ovary | 100% | 6771.63 | 180 / 180 | 98% | 35.78 | 423 / 430 |
adrenal gland | 100% | 8588.66 | 258 / 258 | 98% | 32.66 | 226 / 230 |
esophagus | 97% | 5219.26 | 1402 / 1445 | 100% | 40.04 | 183 / 183 |
liver | 97% | 4930.24 | 220 / 226 | 95% | 22.09 | 385 / 406 |
eye | 0% | 0 | 0 / 0 | 100% | 29.55 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 31.28 | 29 / 29 |
spleen | 100% | 5261.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 66.01 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 80.20 | 1 / 1 |
adipose | 100% | 9157.86 | 1201 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 4441.94 | 1295 / 1335 | 0% | 0 | 0 / 0 |
heart | 93% | 4173.76 | 805 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 4651.94 | 818 / 929 | 0% | 0 | 0 / 0 |
muscle | 39% | 954.97 | 310 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0009443 | Biological process | pyridoxal 5'-phosphate salvage |
GO_0042817 | Biological process | pyridoxal metabolic process |
GO_0042818 | Biological process | pyridoxamine metabolic process |
GO_0005576 | Cellular component | extracellular region |
GO_0035580 | Cellular component | specific granule lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0034774 | Cellular component | secretory granule lumen |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0030170 | Molecular function | pyridoxal phosphate binding |
GO_0008478 | Molecular function | pyridoxal kinase activity |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0031403 | Molecular function | lithium ion binding |
GO_0030955 | Molecular function | potassium ion binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0031402 | Molecular function | sodium ion binding |
Gene name | PDXK |
Protein name | Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) Pyridoxal kinase HCG401289, isoform CRA_e (Pyridoxal kinase) pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) |
Synonyms | PKH C21orf97 PNK PRED79 C21orf124 hCG_401289 |
Description | FUNCTION: Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions. . |
Accessions | A8MV33 ENST00000621478.1 A8MT14 ENST00000467908.1 ENST00000291565.9 [O00764-1] ENST00000327574.4 ENST00000468090.5 [O00764-2] O00764 A0A0B4J2C9 G1UI32 ENST00000398081.5 F2Z2Y4 |