Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipocyte | 9 studies | 33% ± 7% | |
glutamatergic neuron | 8 studies | 42% ± 27% | |
endothelial cell | 7 studies | 27% ± 9% | |
astrocyte | 7 studies | 31% ± 14% | |
GABAergic neuron | 7 studies | 42% ± 23% | |
epithelial cell | 6 studies | 29% ± 12% | |
oligodendrocyte | 6 studies | 26% ± 7% | |
cardiac muscle cell | 4 studies | 21% ± 2% | |
oligodendrocyte precursor cell | 4 studies | 28% ± 7% | |
interneuron | 4 studies | 48% ± 22% | |
GABAergic interneuron | 3 studies | 20% ± 1% | |
microglial cell | 3 studies | 20% ± 1% | |
retinal ganglion cell | 3 studies | 36% ± 11% | |
retina horizontal cell | 3 studies | 20% ± 4% | |
ciliated cell | 3 studies | 17% ± 2% | |
type II pneumocyte | 3 studies | 19% ± 5% | |
macrophage | 3 studies | 18% ± 2% | |
basal cell | 3 studies | 34% ± 16% | |
goblet cell | 3 studies | 27% ± 14% | |
transit amplifying cell | 3 studies | 32% ± 20% | |
neuron | 3 studies | 28% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1747.65 | 1445 / 1445 | 100% | 29.99 | 183 / 183 |
intestine | 100% | 1547.10 | 966 / 966 | 100% | 29.35 | 527 / 527 |
liver | 100% | 1542.27 | 226 / 226 | 100% | 21.35 | 406 / 406 |
prostate | 100% | 1514.33 | 245 / 245 | 100% | 32.76 | 502 / 502 |
stomach | 100% | 1932.31 | 359 / 359 | 100% | 29.41 | 286 / 286 |
breast | 100% | 1783.27 | 459 / 459 | 100% | 42.02 | 1117 / 1118 |
uterus | 100% | 1298.25 | 170 / 170 | 100% | 29.88 | 458 / 459 |
kidney | 100% | 1468.82 | 89 / 89 | 100% | 23.39 | 899 / 901 |
ovary | 100% | 1105.74 | 180 / 180 | 100% | 21.10 | 429 / 430 |
brain | 100% | 1907.26 | 2633 / 2642 | 100% | 31.07 | 705 / 705 |
bladder | 100% | 1709.05 | 21 / 21 | 100% | 25.22 | 502 / 504 |
adrenal gland | 100% | 2309.12 | 258 / 258 | 100% | 24.31 | 229 / 230 |
lung | 99% | 1221.79 | 573 / 578 | 100% | 30.75 | 1155 / 1155 |
thymus | 100% | 1222.49 | 651 / 653 | 99% | 19.85 | 600 / 605 |
pancreas | 99% | 798.29 | 324 / 328 | 99% | 19.21 | 176 / 178 |
skin | 100% | 1538.41 | 1807 / 1809 | 98% | 28.40 | 461 / 472 |
adipose | 100% | 1767.32 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 19.91 | 29 / 29 |
muscle | 100% | 5639.26 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 949.24 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 28.10 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.50 | 1 / 1 |
blood vessel | 100% | 1357.38 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 3547.18 | 838 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 13.90 | 72 / 80 |
peripheral blood | 33% | 590.00 | 309 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006086 | Biological process | acetyl-CoA biosynthetic process from pyruvate |
GO_0045254 | Cellular component | pyruvate dehydrogenase complex |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0034604 | Molecular function | pyruvate dehydrogenase (NAD+) activity |
GO_0016746 | Molecular function | acyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PDHX |
Protein name | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-) Pyruvate dehydrogenase complex component X Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX) |
Synonyms | PDX1 |
Description | FUNCTION: Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. |
Accessions | ENST00000430469.6 [O00330-2] H0YD97 ENST00000533262.1 O00330 ENST00000448838.8 E9PRI6 ENST00000526309.1 ENST00000533550.5 E9PLU0 A0A8C8MSB2 ENST00000227868.9 [O00330-1] |