PDHA2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PDHA2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PDHA2 at tissue level.

III. Associated gene sets

GO_0006086Biological processacetyl-CoA biosynthetic process from pyruvate
GO_0006006Biological processglucose metabolic process
GO_0006090Biological processpyruvate metabolic process
GO_0006099Biological processtricarboxylic acid cycle
GO_0005730Cellular componentnucleolus
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0034604Molecular functionpyruvate dehydrogenase (NAD+) activity
GO_0005515Molecular functionprotein binding
GO_0004739Molecular functionpyruvate dehydrogenase (acetyl-transferring) activity

IV. Literature review

[source]
Gene namePDHA2
Protein namePyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II)
SynonymsPDHAL
DescriptionFUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .

AccessionsENST00000295266.6
P29803